Beyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes

Author(s):Show less -

Morya, Edgard ^{[1, 2]} ; Monte-Silva, Katia ^{[3, 4]} ; Bikson, Marom ^[5] ; Esmaeilpour, Zeinab ^[5] ; Biazoli, Jr., Claudinei Eduardo ^[6] ; Fonseca, Andre ^{[1, 6]} ; Bocci, Tommaso ^[7] ; Farzan, Faranak ^[8] ; Chatterjee, Raaj ^[8] ; Hausdorff, Jeffrey M. ^{[9, 10]} ; da Silva Machado, Daniel Gomes ^[11] ; Brunoni, Andre Russowsky ^[12] ; Mezger, Eva ^[13] ; Moscaleski, Luciane Aparecida ^{[1, 6]} ; Pegado, Rodrigo ^[14] ; Sato, Joao Ricardo ^[6] ; Caetano, Marcelo Salvador ^[6] ; Sa, Katia Nunes ^{[15, 4]} ; Tanaka, Clarice ^{[4, 16]} ; Li, Li Min ^[1] ; Baptista, Abrahao Fontes ^{[15, 1, 6, 4, 16]} ; Okano, Alexandre Hideki ^{[1, 6, 4, 11]}

Affiliation:Show less -

^[1] Univ Estadual Campinas, Brazilian Inst Neurosci & Neurotechnol BRAINN CEP, Campinas, SP - Brazil

^[2] Santos Dumont Inst, Edmond & Lily Safra Int Inst Neurosci, Macaiba, RN - Brazil

^[3] Univ Fed Pernambuco, Recife, PE - Brazil

^[4] Univ Fed Pernambuco UFPE, NAPeN, EBMSP, Univ Fed ABC UFABC, Univ Sao Paulo USP, Univ Cidade, Santo Andre, SP - Brazil

^[5] CUNY City Coll, New York, NY 10031 - USA

^[6] Univ Fed ABC UFABC, Ctr Math Comp & Cognit CMCC, Alameda Univ, 3 Anchieta, Bloco Delta Sala 257, BR-09606070 Sao Bernardo Do Campo, SP - Brazil

^[7] Univ Milan, Int Med Sch, Dept Hlth Sci, Aldo Ravelli Ctr Neurotechnol & Expt Brain Therap, Milan - Italy

^[8] Simon Fraser Univ, Sch Mechatron Syst Engn, Surrey, BC - Canada

^[9] Tel Aviv Univ, Sackler Fac Med, Dept Phys Therapy, Tel Aviv - Israel

^[10] Tel Aviv Univ, Sagol Sch Neurosci, Tel Aviv - Israel

^[11] Univ Estadual Londrina, Grad Program Phys Educ, Londrina, Parana - Brazil

^[12] Univ Sao Paulo, Lab Neurosci LIM27, Sao Paulo, SP - Brazil

^[13] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Psychiat & Psychotherapy, Munich - Germany

^[14] Univ Fed Rio Grande do Norte, Grad Program Rehabil Sci, Santa Cruz, RN - Brazil

^[15] Escola Bahiana Med & Saude Publ, Salvador, BA - Brazil

^[16] Univ Sao Paulo, Lab Invest Med 54, Sao Paulo, SP - Brazil

• Document type: Review article
• Source: JOURNAL OF NEUROENGINEERING AND REHABILITATION; v. 16, n. 1 NOV 15 2019.
• Web of Science Citations: 1

Abstract

Transcranial Direct Current Stimulation (tDCS) is a non-invasive technique used to modulate neural tissue. Neuromodulation apparently improves cognitive functions in several neurologic diseases treatment and sports performance. In this study, we present a comprehensive, integrative review of tDCS for motor rehabilitation and motor learning in healthy individuals, athletes and multiple neurologic and neuropsychiatric conditions. We also report on neuromodulation mechanisms, main applications, current knowledge including areas such as language, embodied cognition, functional and social aspects, and future directions. We present the use and perspectives of new developments in tDCS technology, namely high-definition tDCS (HD-tDCS) which promises to overcome one of the main tDCS limitation (i.e., low focality) and its application for neurological disease, pain relief, and motor learning/rehabilitation. Finally, we provided information regarding the Transcutaneous Spinal Direct Current Stimulation (tsDCS) in clinical applications, Cerebellar tDCS (ctDCS) and its influence on motor learning, and TMS combined with electroencephalography (EEG) as a tool to evaluate tDCS effects on brain function. (AU)

• FAPESP's process: 14/10134-7 - Non invasive brain stimulation, physical exercise and reward system
• Grantee: Alexandre Hideki Okano
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 13/10187-0 - Neuromodulation and Brain Regulation of Physical Exercise
• Grantee: Alexandre Hideki Okano
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology
• Grantee: Fernando Cendes
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 14/50909-8 - INCT 2014: Behavior, Cognition and Teaching (INCT-ECCE): relational learning and symbolic functioning
• Grantee: Deisy das Graças de Souza
• Support Opportunities: Research Projects - Thematic Grants