| Full text | |
| Author(s): |
Santos, Elias B.
[1]
;
Valsecchi, Chiara
[2]
;
Goncalves, Jaderson L. S.
[2]
;
Avila, Luis F.
[3]
;
Menezes, Jacson W.
[2]
Total Authors: 5
|
| Affiliation: | [1] Univ Fed Sao Paulo, LQANano, BR-12231280 Sao Jose Dos Campos, SP - Brazil
[2] Fed Univ Pampa, Engn Dept, BR-97546550 Alegrete, RS - Brazil
[3] Univ Estadual Campinas, Sch Technol, Appl Opt Lab, BR-13484350 Limeira, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | SENSORS; v. 19, n. 20 OCT 2 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
Single-drop microextraction (SDME) was coupled with surface-enhanced Raman scattering (SERS) to provide sample extraction and pre-concentration for detection of analyte at low concentrations. A gold nanohole array substrate (AuNHAS), fabricated by interference lithography, was used as SERS substrate and para-mercaptobenzoic acid (p-MBA) was tested as a probe molecule, in the concentration range 10(-8)-10(-4) mol L-1. With this approach, a limit of 10(-7) mol L-1 was clearly detected. To improve the detection to lower p-MBA concentration, as 10(-8) mol L-1, the SDME technique was applied. The p-MBA Raman signature was detected in two performed extractions and its new concentration was determined to be similar to 4.6 x 10(-5) mol L-1. This work showed that coupling SDME with SERS allowed a rapid (5 min) and efficient pre-concentration (from 10 8 mol L-1 to 10(-5) mol L-1), detection, and quantification of the analyte of interest, proving to be an interesting analytical tool for SERS applications. (AU) | |
| FAPESP's process: | 15/16573-5 - Plasmonic nanoparticles of silver, gold, and copper: synthetic methods, preparation of reproducible plasmonic and SERS sensors for environmental applications |
| Grantee: | Elias de Barros Santos |
| Support Opportunities: | Regular Research Grants |