Enantioseparation of pesticides: A critical review

Author(s)

Carrao, Daniel Blascke ^[1] ; Perovani, Icaro Salgado ^[1] ; Perez de Albuquerque, Nayara Cristina ^[1] ; Moraes de Oliveira, Anderson Rodrigo ^{[1, 2]}

Affiliation

^[1] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto, SP - Brazil

^[2] UNESP, Inst Chem, Natl Inst Alternat Technol Detect Toxicol Evaluat, POB 355, BR-14800900 Araraquara, SP - Brazil

• Document type: Review article
• Source: TRAC-TRENDS IN ANALYTICAL CHEMISTRY; v. 122, JAN 2020.
• Web of Science Citations: 0

Abstract

The potential of chiral pesticides to exhibit stereoselective behavior in regards to activity, toxicity, degradation, bioaccumulation, and/or metabolism has inspired numerous studies, e.g., several works have investigated the contamination of water, food, and soil by chiral pesticides and the consequences of non-targeted species (including human) exposure to these chemicals. As these studies typically rely on enantioselective separation methods such as liquid chromatography, supercritical fluid chromatography, gas chromatography, and capillary electromigration techniques, this review aims to provide a critical point of view on these analytical techniques used for the enantioselective analysis of pesticides. Accordingly, we selected papers from different areas and several issues (as chiral stationary phases or chiral selectors, mobile phases, and method detectability) regarding each technique were critically discussed. Finally, we outlined the future trends for each technique in the chiral analysis of pesticides. (C) 2019 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 14/50945-4 - INCT 2014: National Institute for Alternative Technologies of Detection, Toxicological Evaluation and Removal of Micropollutants and Radioactivies
• Grantee: Maria Valnice Boldrin
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 16/15680-5 - Enantioselective in vitro studies of metabolism, enzymatic inhibition and toxicity of the pesticide fipronil
• Grantee: Daniel Blascke Carrão
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 18/14668-7 - Development of a microfluidic analytical device for on-site quantification of pesticides after spraying in plants with citrus greening disease
• Grantee: Daniel Blascke Carrão
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• FAPESP's process: 18/07534-4 - Development of chromatographic / electrophoretic methods to be further applied in in vitro enzymatic inhibition studies and prediction of drug interactions of chiral pesticides - Phase 2
• Grantee: Anderson Rodrigo Moraes de Oliveira
• Support Opportunities: Regular Research Grants