Synthesis, characterization, and thermoanalytical study of aceclofenac of light lanthanides in the solid state (La, Ce, Pr, and Nd)

Author(s)

de Souza, Adrian Santos ^[1] ; Ekawa, Bruno ^[2] ; de Carvalho, Claudio Teodoro ^[1] ; Teixeira, Jose Augusto ^[3] ; Ionashiro, Massao ^[2] ; Denck Colman, Tiago Andre ^[1]

Affiliation

^[1] UFCD, Fed Univ Grande Dourados, Dourados, MS - Brazil

^[2] UNESP, Inst Chem, Araraquara, SP - Brazil

^[3] Fed Inst Educ Sci & Technol Parana, Paranavai, PR - Brazil

• Document type: Journal article
• Source: Thermochimica Acta; v. 683, JAN 2020.
• Web of Science Citations: 0

Abstract

Lanthanide aceclofenac compounds were synthesized by the addition of lanthanide nitrate aqueous solution to aceclofenac-acetone solution. The compounds obtained in the solid state were characterized by thermal and spectroscopic studies, as well as by complementary x-ray diffraction data. The metal-ligand stoichiometric ratio was defined by simultaneous thermogravimetry and differential scanning calorimetry (TG-DSC) as {[}Ln (Acec)(3)center dot nH(2)O], where Ln represents the metal centre (La, Ce, Pr, or Nd) and Acec represents the ligand, with n = 4(La), 3(Ce), and 2.5(Pr, Nd). TG-DSC and Fourier transform infrared spectroscopy (FTIR) data also allowed for determination of the thermal behaviour and possible coordination modes between the metal and the ligand. (AU)

• FAPESP's process: 13/09022-7 - Thermoanalytical studies, synthesis and characterization of the solid co-crystals of antibiotics (fluoroquinolones) with some co-formers
• Grantee: Massao Ionashiro
• Support Opportunities: Regular Research Grants
• FAPESP's process: 06/06951-3 - Synthesis, characterization and thermoanalytical study of lanthanum (III), lanthanides (III) and yttrium (III) with 2-methoxycinnamilidenepiruvate
• Grantee: Massao Ionashiro
• Support Opportunities: Regular Research Grants