Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Simple GFAAS Method for Determination of Pb, As, and Cd in Cannabidiol Extracts Used for Therapeutic Purposes

Full text
Author(s):
Nascimento, Patricia A. [1] ; Schultz, Juliana [1] ; Gonzalez, Mario H. [2] ; Oliveira, Andrea [1]
Total Authors: 4
Affiliation:
[1] Univ Fed Parana UFPR, Dept Quim, BR-81531980 Curitiba, Parana - Brazil
[2] Univ Estadual Paulista, UNESP, Dept Quim & Ciencias Ambientais, BR-15054000 Sao Jose Do Rio Preto, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 31, n. 5, p. 894-903, MAY 2020.
Web of Science Citations: 0
Abstract

Cannabis sativa has many promising medicinal applications for the mitigation, or even cure, of chronic diseases. The high bioaccumulation potential of C. sativa enables its use for the phytoremediation and detoxification of soil, may increase the levels of inorganic elements in products such as cannabidiol (CBD) extracts being necessary the evaluation/monitoring of the level of inorganic components, mainly the toxic species in these formulations. An analytical method employing graphite furnace atomic absorption spectrometry (GFAAS) was developed for the quantification of Pb, As, and Cd in commercial CBD extracts and homemade samples. The alkaline solubilization was employed in agreement with the external analytical curve, in a robust method. The limits of quantification were 0.26 (Pb), 0.067 (As), and 0.011 µg g-1 (Cd), with satisfactory accuracy (80-120%) and relative standard deviation (RSD) values < 7%. The CBD extracts presented levels of Pb, As and Cd below the maximum limits established by regulatory agencies. (AU)

FAPESP's process: 13/23886-4 - Study on selectivity of hydrogenolysis / reductive hydrogenation processes of sugarcane bagasse under supercritical state catalyzed by structured metal oxides
Grantee:Mauricio Boscolo
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Regular Program Grants
FAPESP's process: 17/09520-8 - Sucrose pyridinic esters: synthesis, characterization and antimicrobial activity: evaluation of the synthesis parameters by acoustic cavitation
Grantee:Jorge Andrés Mora Vargas
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 17/13230-5 - Partial ethanol reforming: stability and selectivity of mix metal amphoteric oxides as catalysts for atmospheric pressure flow reaction
Grantee:Mauricio Boscolo
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Regular Program Grants
FAPESP's process: 17/18531-3 - Green analytical chemistry: from sample preparation to trace element determinations by inductively coupled plasma mass spectrometry (ICP-MS)
Grantee:Mario Henrique Gonzalez
Support Opportunities: Regular Research Grants
FAPESP's process: 15/08873-9 - Assessment of arsenic's bioaccumulation and associated risks from fish consumption in Brazil
Grantee:Mario Henrique Gonzalez
Support Opportunities: Regular Research Grants