Emerging applications of paper-based analytical devices for drug analysis: A review

Author(s)

Noviana, Eka ^{[1, 2]} ; Carrao, Daniel Blascke ^{[3, 1]} ; Pratiwi, Rimadani ^[4] ; Henry, Charles S. ^[1]

Affiliation

^[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 - USA

^[2] Univ Gadjah Mada, Fac Pharm, Dept Pharmaceut Chem, Yogyakarta 55281 - Indonesia

^[3] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Ribeirao Preto, SP - Brazil

^[4] Univ Padjajaran, Fac Pharm, Dept Pharmaceut Anal & Med Chem, Bandung 45363 - Indonesia

• Document type: Review article
• Source: Analytica Chimica Acta; v. 1116, p. 70-90, JUN 15 2020.
• Web of Science Citations: 0

Abstract

The use of paper microfluidics to perform chemical measurements for various analytical applications has gained interest over the last decade. One of the growing applications of these platforms is for the qualitative and quantitative determination of drugs. The low cost and self-pumping ability of paper microfluidics are attractive for developing analytical tools capable of on-site drug screening. This review aims to present the unique features of microfluidic paper-based analytical devices (mPADs) that offer advantages to pharmaceutical analysis and evaluate the state-of-the-art technologies and applications of the platform for drug analysis in research and real-world settings. The current challenges and potential future directions of the field are also highlighted. (C) 2020 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 18/14668-7 - Development of a microfluidic analytical device for on-site quantification of pesticides after spraying in plants with citrus greening disease
• Grantee: Daniel Blascke Carrão
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate