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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Uric acid electrochemical sensing in biofluids based on Ni/Zn hydroxide nanocatalyst

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Author(s):
Azeredo, Nathalia F. B. [1, 2] ; Goncalves, Josue M. [1, 3] ; Rossini, Pamela O. [1, 3] ; Araki, Koiti [1, 3] ; Wang, Joseph [2] ; Angnes, Lucio [1, 3]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Inst Chem, Dept Fundamental Chem, Sao Paulo - Brazil
[2] Univ Calif San Diego, Dept Nanoengn, La Jolla, CA 92093 - USA
[3] Wang, Joseph, Univ Calif San Diego, Dept Nanoengn, La Jolla, CA 92093 USA.Azeredo, Nathalia F. B., Univ Sao Paulo, Inst Chem, Dept Fundamental Chem, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Microchimica Acta; v. 187, n. 7 JUN 9 2020.
Web of Science Citations: 0
Abstract

A highly sensitive sensor for quantification of uric acid (UA) directly in body fluids (saliva and sweat) is reported, working at a potential as low as 0.0 V vs Ag/AgCl. New mixed hydroxide materials exhibiting stable electrocatalytic responses from alkaline to acidic media were prepared, their structure was thoroughly characterized, and the electrochemical properties of the modified FTO (fluorine-doped tin oxide) electrodes were evaluated for UA determination by cyclic voltammetry, chronoamperometry,and batch injection analysis. A very low limit of detection (2.3 x 10(-8) mol L-1) with good repeatability (RSD = 3.2% for 30 successive analyses)was achieved based on a fast and simple BIA procedure. Finally, alpha-Ni0.75Zn0.25(OH)(2)screen-printed electrodes (SPE) were developed for the measurement of UA directly in real saliva and sweat samples, without interference of ascorbic acid, acetaminophen, lactate,and glucose at their typical concentrations present in those body fluids, revealing high potential for application as disposable sensors in biological systems. (AU)

FAPESP's process: 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis
Grantee:Lauro Tatsuo Kubota
Support type: Research Projects - Thematic Grants
FAPESP's process: 17/13137-5 - Formation and properties of hemiesters of carbonic acid in aqueous medium
Grantee:Claudimir Lucio Do Lago
Support type: Research Projects - Thematic Grants
FAPESP's process: 18/21489-1 - Supramolecular nanotechnology: design, materials and devices
Grantee:Henrique Eisi Toma
Support type: Research Projects - Thematic Grants
FAPESP's process: 18/16896-7 - Development of amperometric and impedimetric sensors based on double hydroxides of nickel and vanadium (alpha-NixV1-x(OH)2) and their nanocomposites with expandable graphite/graphene
Grantee:Josué Martins Gonçalves
Support type: Scholarships in Brazil - Post-Doctorate