Abstract
Nanotechnology based on a supramolecular approach is the subject of this research proposal. New supramolecular structures encompassing metal-polypyridines, tetrapyridylporphyrins, tetraaza-porphyrazines and triangular Ru3O clusters are being assembled, aiming the generation of high performance electro/photo catalysts, sensors and photoelectrochemical cells. Nanoparticles bearing a supramolecular design are being elaborated from plasmonic (Ag, Au), semiconductor (TiO2), superparamagnetic (Fe3O4 and g-Fe2O3) and quantum dots (CdTe, C*) cores, which are stabilized with suitable protecting coatings, such as of SiO2 and polymers. Then, they are modified with specific functional agents, aiming biological and medical applications, and the development of new, green, biotechnological and hydrometallurgical processes. New supramolecular dye TiO2 cells incorporating a vectorial design are being developed. Superparamagnetic and plasmonic gold nanoparticles are being attached to screen printed gold electrodes for performing magnetically confined electroanalysis and in situ SERS spectroelectrochemistry. Chelating superparamagnetic nanoparticles are being used for the capture and processing of metal ions, based on magnetic nanohydrometallurgy, including the separation of rare earth elements. Enzymes immobilized onto superparamagnetic nanoparticles are being applied in synthetic chemistry and enantiomeric resolution of chemical species. Finally, multifunctional engineered nanoparticles are being developed for a wide variety of medical applications, including theranostic and MRI contrasting agents. The proposal encompasses two research groups with 35 participants, and involves strong national and international collaboration with many different institutions and industries. (AU)
Scientific publications
(26)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DEDA, DAIANA K.;
CARDOSO, ROBERTA M.;
KAWASSAKI, RODRIGO K.;
DE OLIVEIRA, ANDRE R.;
TOMA, SERGIO H.;
BAPTISTA, MAURICIO S.;
ARAKI, KOITI.
Cytotoxicity of Methotrexate Conjugated to Glycerol Phosphate Modified Superparamagnetic Iron Oxide Nanoparticles.
Journal of Nanoscience and Nanotechnology,
v. 21,
n. 3,
p. 1451-1461,
MAR 2021.
Web of Science Citations: 0.
PEFFI FERREIRA, LUIS FERNANDO;
MAZZI DE OLIVEIRA, THAYNA;
TOMA, SERGIO HIROSHI;
TOYAMA, MARCOS MAKOTO;
ARAKI, KOITI;
AVANZI, LUIS HUMBERTO.
Superparamagnetic iron oxide nanoparticles (SPIONs) conjugated with lipase Candida antarctica A for biodiesel synthesis.
RSC ADVANCES,
v. 10,
n. 63,
p. 38490-38496,
OCT 21 2020.
Web of Science Citations: 0.
ROMANO, MARIANA;
UCHIYAMA, MAYARA K.;
CARDOSO, ROBERTA M.;
TOMA, SERGIO H.;
BAPTISTA, MAURICIO S.;
ARAKI, KOITI.
Nitric oxide inhibition of lipopolysaccharide-stimulated RAW 247.6 cells by ibuprofen-conjugated iron oxide nanoparticles.
Nanomedicine,
v. 15,
n. 25,
p. 2475-2492,
SEP 2020.
Web of Science Citations: 0.
GONCALVES, JOSUE M.;
DA SILVA, MATHEUS L.;
TOMA, HENRIQUE E.;
ANGNES, LUCIO;
MARTINS, PAULO R.;
ARAKI, KOITI.
Trimetallic oxides/hydroxides as hybrid supercapacitor electrode materials: a review.
JOURNAL OF MATERIALS CHEMISTRY A,
v. 8,
n. 21,
p. 10534-10570,
JUN 7 2020.
Web of Science Citations: 0.
KUMAR, ABHISHEK;
FURTADO, VINICIUS L.;
GONCALVES, JOSUE M.;
BANNITZ-FERNANDES, RENATA;
NETTO, LUIS EDUARDO S.;
ARAKI, KOITI;
BERTOTTI, MAURO.
Amperometric microsensor based on nanoporous gold for ascorbic acid detection in highly acidic biological extracts.
Analytica Chimica Acta,
v. 1095,
p. 61-70,
JAN 25 2020.
Web of Science Citations: 0.
KUMAR, ABHISHEK;
GONCALVES, JOSUE M.;
LIMA, ALAN R.;
MATIAS, TIAGO A.;
NAKAMURA, MARCELO;
BERNARDES, JULIANA S.;
ARAKI, KOITI;
BERTOTTI, MAURO.
Efficient and methanol resistant noble metal free electrocatalyst for tetraelectronic oxygen reduction reaction.
Electrochimica Acta,
v. 326,
DEC 5 2019.
Web of Science Citations: 0.
SANTOS, JONNATAN J.;
TOMA, SERGIO H.;
MONEZI, NATALIA M.;
ANDO, ROMULO A.;
CORIO, PAOLA;
ARAKI, KOITI.
Selecting the Mechanism of Surface-Enhanced Raman Scattering Effect using Shell Isolated Nanoparticles and an Oxo-Triruthenium Acetate Cluster Complex.
Inorganic Chemistry,
v. 58,
n. 15,
p. 10399-10407,
AUG 5 2019.
Web of Science Citations: 0.