Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Trihaloisocyanuric acids in ethanol: an eco-friendly system for the regioselective halogenation of imidazo-heteroarenes

Full text
Author(s):
Neto, Jose S. S. [1] ; Balaguez, Renata A. [2] ; Franco, Marcelo S. [1, 3] ; de Sa Machado, Victor C. [1, 3] ; Saba, Sumbal [4] ; Rafique, Jamal [5] ; Galetto, Fabio Z. [2] ; Braga, Antonio L. [1, 3]
Total Authors: 8
Affiliation:
[1] Univ Fed Santa Catarina, LabSelen Dept Quim, BR-88040900 Florianopolis, SC - Brazil
[2] Univ Fed Santa Catarina, Dept Quim, BR-88040900 Florianopolis, SC - Brazil
[3] Rafique, Jamal, Univ Fed Mato Grosso UFMS, Inst Quim, BR-79074460 Campo Grande, MS, Brazil.Neto, Jose S. S., Univ Fed Santa Catarina, LabSelen Dept Quim, BR-88040900 Florianopolis, SC - Brazil
[4] Univ Fed ABC, Ctr Ciencias Nat & Humanas CCNH, BR-09210580 Santo Andre, SP - Brazil
[5] Univ Fed Mato Grosso UFMS, Inst Quim, BR-79074460 Campo Grande, MS - Brazil
Total Affiliations: 5
Document type: Journal article
Source: GREEN CHEMISTRY; v. 22, n. 11, p. 3410-3415, JUN 7 2020.
Web of Science Citations: 1
Abstract

Herein, we describe an efficient, rapid and benign protocol for the direct C(sp(2))-H bond halogenation (Cl, Br, I) of 2-arylimidazo{[}1,2-a]pyridines using trihaloisocyanuric acids in ethanol. Furthermore, this sustainable protocol was successfully extended to imidazopyrimidine, imidazothiazole and indazole heterocycles showing the broadness of this useful approach. (AU)

FAPESP's process: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
Grantee:Arlene Gonçalves Corrêa
Support Opportunities: Research Grants - Research Centers in Engineering Program