Effect of two corticotomy protocols on periodontal tissue and orthodontic movement

Author(s)

Marcelo Lelis ZUPPARDO ^[1] ; Milton SANTAMARIA JR ^[2] ; Camila Lopes FERREIRA ^[3] ; Mariéllen LONGO ^[4] ; Joni Augusto CIRELLI ^[5] ; Mauro Pedrine SANTAMARIA ^[6] ; Maria Aparecida Neves JARDINI ^[7]

Affiliation

^[1] Universidade Estadual Paulista - Brasil

^[2] UNIARARAS. Centro Universitário Hermínio Ometto. Programa de Pós-Graduação em Ortodontia - Brasil

^[3] Universidade Estadual Paulista - Brasil

^[4] Universidade Estadual Paulista - Brasil

^[5] Universidade Estadual Paulista. Faculdade de Odontologia - Brasil

^[6] Universidade Estadual Paulista - Brasil

^[7] Universidade Estadual Paulista - Brasil

• Document type: Journal article
• Source: Journal of Applied Oral Science; v. 28, 2020-07-03.

Abstract

Abstract Objective To compare two corticotomy surgical protocols in rats to verify whether they alter conventional orthodontic movement. Methodology Sixty Wistar rats were divided into three groups – orthodontic movement (CG), orthodontic movement and corticotomy (G1) and orthodontic movement with corticotomy and decortication (G2) – and euthanized after 7 and 14 days. Tooth movement (mm), bone volume fraction and bone volume ratio to total volume (BV/TV), and bone mineral density (BMD) were evaluated by micro-CT. The total amount of bone was measured in square millimeters and expressed as the percentage of bone area in the histomorphometry. The number of positive TRAP cells and RANK/RANKL/OPG interaction were also investigated. Results Day 14 showed a statistically significant difference in orthodontic tooth movement in CG compared with G1 (7.52 mm; p=0.009) and G2 (7.36 mm; p=0.016). A micro-CT analysis revealed a difference between CG, G1 and G2 regarding BV/TV, with G1 and G2 presenting a lower BV/TV ratio at 14 days (0.77 and 0.73 respectively); we found no statistically significant differences regarding BMD. There was a difference in the total amount of bone in the CG group between 7 and 14 days. At 14 days, CG presented a significantly higher bone percentage than G1 and G2. Regarding TRAP, G2 had more positive cells at 7 and 14 days compared with CG and G1. Conclusion Corticotomy accelerates orthodontic movement. Decortication does not improve corticotomy efficiency. (AU)

• FAPESP's process: 16/17141-4 - Radiographic aspects of orthodontic movement of molars submitted to corticotomy: studies in animals
• Grantee: Nicole Berton de Moura
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 15/26523-5 - Corticotomy effect on orthodontic tooth movement. Histomorphometric and immunohistochemical study in rats.
• Grantee: Maria Aparecida Neves Jardini
• Support Opportunities: Regular Research Grants