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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Primary intraosseous CD9-positive B-cell lymphoblastic lymphoma of the maxilla affecting a pediatric patient: Immunohistochemical and in situ hybridization analysis

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Author(s):
Silveira, Heitor Albergoni [1, 2] ; Sousa, Lucas Moura [3] ; Silva, Evanio Vilela [1, 2] ; Almeida, Lana Kei Yamamoto [4] ; Sverzut, Cassio Edvard [3] ; Trivellato, Alexandre Elias [3] ; Leon, Jorge Esquiche [2]
Total Authors: 7
Affiliation:
[1] Sao Paulo State Univ Unesp, Araraquara Dent Sch, Oral Med, Dept Diag & Surg, Araraquara, SP - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Dent Sch FORP USP, Dept Stomatol Publ Oral Hlth & Forens Dent, Oral Pathol, Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Dent Sch FORP USP, Dept Oral & Maxillofacial Surg & Periodontol, Oral & Maxillofacial Surg, Ribeirao Preto, SP - Brazil
[4] Univ Sao Paulo, Ribeirao Preto Dent Sch FORP USP, Dept Pediat Dent, Ribeirao Preto, SP - Brazil
Total Affiliations: 4
Document type: Letter
Source: Oral Oncology; v. 108, SEP 2020.
Web of Science Citations: 0
Abstract

Lymphoblastic lymphoma (LBL) is a clinically aggressive disease, representing approximately 2% of all non-Hodgkin lymphoma cases. In the oral and maxillofacial (OMF) region, approximately 39 cases, diagnosed as LBL, acute lymphoblastic leukemia (ALL) or ALL/LBL, have been reported to date. Noteworthy, the CD9 expression, which indicates a poor outcome in ALL, has not been reported in LBL and lymphoblastic neoplasms of the OMF region. Herein, we report an additional maxillary intraosseous B-cell LBL, affecting a 14-year-old girl, which also showed positivity for CD9, Bcl-6 and MUM1/IRF4. Aiming at diagnostic and prognostic criteria, further studies focusing CD9 expression in LBL is recommended. (AU)

FAPESP's process: 18/12734-2 - Comparative immunohistochemical characterization of dendritic cell subgroups and viral oncogenesis in oral and oropharyngeal squamous cell carcinoma
Grantee:Heitor Albergoni da Silveira
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 16/11419-0 - Clinicopathological correlation of the degree of differentiation, tetraspanin expression, viral agents and cell proliferation in a large sample of squamous cell carcinoma of the head and neck region.
Grantee:Jorge Esquiche León
Support Opportunities: Regular Research Grants