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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

LIG-Doctor: Efficient patient trajectory prediction using bidirectional minimal gated-recurrent networks

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Author(s):
Rodrigues-, Jr., Jose F. [1] ; Gutierrez, Marco A. [2] ; Spadon, Gabriel [1] ; Brandoli, Bruno [3] ; Amer-Yahia, Sihem [4]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Inst Math Sci & Comp, Av Trab Sao Carlense 400, Sao Carlos, SP - Brazil
[2] Univ Sao Paulo, Heart Inst, Av Dr Eneas C Aguiar 44, Sao Paulo, SP - Brazil
[3] Dalhousie Univ, Inst Big Data Analyt, 6050 Univ Ave, Halifax, NS - Canada
[4] Univ Grenoble Alpes, IMAG, CNRS, 700 Av Cent, St Martin Dheres - France
Total Affiliations: 4
Document type: Journal article
Source: INFORMATION SCIENCES; v. 545, p. 813-827, FEB 4 2021.
Web of Science Citations: 0
Abstract

The interest for patient trajectory prediction, a sort of computer-aided medicine, has steadily increased with the pace of artificial intelligence innovation. Notwithstanding, the design of effective systems able to predict clinical outcomes based on the history of a patient is far from trivial. Works so far are based on neural architectures with low performance, especially when using low-cardinality datasets; alternatively, complex inference approaches are hard to reproduce and/or extrapolate as they are designed for very specific circumstances. We introduce LIG-Doctor, an artificial neural network architecture based on two Minimal Gated Recurrent Unit networks functioning in a bidirectional parallel manner, benefiting from temporal events both forward and backward. In comparison to state-of-the-art works, consistent improvements were achieved in prognosis prediction, as assessed with metrics Recall@k, Precision@k, F1-score, and AUC-ROC. Besides the detailed delineation of our architecture, a sequence of experiments is reported with insights that progressively guided design decisions to inspire future works on similar problems. Our results shall contribute to the improvement of computer-aided medicine and, more generally, to processes related to the design of neural network architectures. (C) 2020 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 18/17620-5 - Preventive medicine by means of deep learning techniques applied in healthcare prognosis
Grantee:José Fernando Rodrigues Júnior
Support Opportunities: Scholarships abroad - Research
FAPESP's process: 16/17078-0 - Mining, indexing and visualizing Big Data in clinical decision support systems (MIVisBD)
Grantee:Agma Juci Machado Traina
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 17/08376-0 - Analysis and improvement of urban systems using digital maps in the form of complex networks
Grantee:Gabriel Spadon de Souza
Support Opportunities: Scholarships in Brazil - Doctorate