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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes): Absence of Changes in Maternal Reproductive Performance and Embryofetal Development In Vivo

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Author(s):
Camargo, Isabella Ferreira [1] ; Ajala Gaetano, Erika Leao [1] ; Pickler, Thaisa Borim [1] ; Gerenutti, Marli [1] ; Grotto, Denise [1]
Total Authors: 5
Affiliation:
[1] Univ Sorocaba Uniso, Rodovia Raposo Tavares Km 92-5, BR-18023000 Sorocaba, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: International Journal of Medicinal Mushrooms; v. 22, n. 8, p. 781-792, 2020.
Web of Science Citations: 0
Abstract

The shiitake culinary-medicinal mushroom Lentinus edodes (=Lentinula edodes) has been used as a nutritional complement. This study evaluated, through reprotox tests, the consumption of L. edodes in pregnant rats, considering it as a functional food. Pregnant rats were daily exposed to L. edodes before implantation (LeB)-from 1 to 19 days of gestation, and after implantation (LeA)-from 9 to 19 days of gestation, compared with controls. On the 20th day of gestation, cesarean sections were performed. Blood was collected and hematological parameters (hemoglobin, hematocrit, white and red blood cells and platelets) were analyzed. Moreover, albumin, calcium, creatine kinase, alkaline phosphatase, transferases, creatinine, urea, triglycerides, cholesterol, lipase, glucose, and insulin were assessed in serum. Organs were collected and weighed, and the fetuses were analyzed morphologically by body measurements. The consumption of L. edodes reduced triglycerides levels and there were no changes in maternal weight, biochemical and hematological parameters, organ weight, and reproductive capacity. There were no morphological changes in the fetuses' body measurements, suggesting possible safety in ingestion of mushroom. Reprotox tests used to evaluate the daily consumption of L. edodes points out potentiality as a functional food, suggesting safety during the gestational period. (AU)

FAPESP's process: 15/24566-9 - Pre-clinical studies with Agaricus blazei, Lentinula edodes and Ganoderma lucidum, aiming to reduce the maternal and fetal damage caused by gestational diabetes.
Grantee:Marli Gerenutti
Support Opportunities: Regular Research Grants