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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Phenotypic detection of quorum sensing inhibition inPseudomonas aeruginosapyoverdine and swarming by volatile organic products

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Author(s):
Ramirez-Rueda, Roman Y. [1, 2, 3] ; Salvador, Marcos J. [1, 2]
Total Authors: 2
Affiliation:
[1] Univ Campinas UNICAMP, Inst Biol, PPG BTPB, Dept Plant Biol, Postal Box 6109, BR-13083970 Campinas, SP - Brazil
[2] Univ Campinas UNICAMP, Inst Biol, PPG BV, Postal Box 6109, BR-13083970 Campinas, SP - Brazil
[3] Pedag & Technol Univ Colombia, Fac Hlth Sci, Postal Box 0387437173, Calle 24 5-63, Tunja - Colombia
Total Affiliations: 3
Document type: Journal article
Source: FUTURE MICROBIOLOGY; v. 15, n. 12, p. 1147-1156, AUG 2020.
Web of Science Citations: 0
Abstract

Aim:To determine phenotypically the anti quorum-sensing (QS) activity of 30 volatile organic products (VOPs) through the inhibition of swarming motility and pyoverdine production inPseudomonas aeruginosa.Materials \& methods:Twenty-four essential oils and six small volatile organic compounds randomly selected were screened for their anti-QS activity by violacein inhibition onChromobacterium violaceum. The VOPs with positive results were subsequently evaluated for swarming motility and pyoverdine production onP. aeruginosadetermining the colony diameter and fluorescence under UV light, respectively.Results:Fifty percent of VOPs tested showed strong violacein inhibition, 40% presented anti-swarming activity and 33% inhibited pyoverdine production.Conclusion:Our data demonstrate that VOPs have a great potential to inhibit virulence factors mediated by QS inP. aeruginosa (AU)

FAPESP's process: 15/03726-8 - Integrated chemical and biological study in the search for bioactive substances in plants* and development of analytical procedures. *(Amaranthaceae, Gesneriaceae, Myrtaceae e Annonaceae)
Grantee:Marcos José Salvador
Support Opportunities: Regular Research Grants