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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Enzyme Stimuli-Responsive Nanoparticles for Bioinsecticides: An Emerging Approach for Uses in Crop Protection

Full text
Author(s):
Camara, Marcela Candido [1] ; Monteiro, Renata Aparecida [1] ; Carvalho, Lucas Braganca [1] ; Oliveira, Jhones Luiz [1] ; Fraceto, Leonardo F. [1]
Total Authors: 5
Affiliation:
[1] Sao Paulo State Univ UNESP, Inst Sci & Technol, BR-18087180 Aparecidinha, Sorocaba - Brazil
Total Affiliations: 1
Document type: Journal article
Source: ACS SUSTAINABLE CHEMISTRY & ENGINEERING; v. 9, n. 1, p. 106-112, JAN 11 2021.
Web of Science Citations: 1
Abstract

The encapsulation of pesticides in systems responsive to enzymes allow for greater selectivity and specificity in pest control, in addition to contributing to reducing the impact on nontarget organisms and the environment. Therefore, the objective of this study was to investigate the synthesis of zein nanoparticles loaded with a mixture of botanical insecticides with release triggered by proteolytic enzymes found in the midguts of insects and larvae. The synthesis of the nanoparticles was carried out using the antisolvent precipitation method. Nanoformulations were characterized according to size, zeta potential, encapsulation efficiency, matrix and active ingredients interaction, and morphology. The enzymatic degradation was then studied. Nanoformulations have excellent encapsulation efficiency, greater than 95%, and stability over 60 days. The enzymatic tests showed significant reduction of the initial concentration of nanoparticles in 60 min and improved the release of geraniol, which increased from 15% to 56% in the presence of trypsin. Thus, the proteolytic enzymes were able to break down zein nanoparticles and stimulate the release of active ingredients providing a significant perspective for the control of crop insects. (AU)

FAPESP's process: 18/23608-8 - Development of labelled nanopesticides aiming studies of mechanism of action and toxicity
Grantee:Lucas Bragança de Carvalho
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 18/21142-1 - Encapsulation of Bacillus thuringiensis (Bacillales: Bacillaceae) in polymeric microparticles and association with nanoencapsulated chemical agent: evaluation of biological activity and mechanisms of action
Grantee:Jhones Luiz de Oliveira
Support Opportunities: Scholarships in Brazil - Post-Doctoral