Effects of experimentally induced muscle pain on endurance performance: A proof-of-concept study assessing neurophysiological and perceptual responses

Author(s)

Canestri, Raul ^[1] ; Franco-Alvarenga, Paulo Estevao ^{[1, 2, 3]} ; Brietzke, Cayque ^{[1, 2]} ; Vinicius, Italo ^[1] ; Smith, Samuel A. ^[4] ; Mauger, Alexis R. ^[4] ; Goethel, Marcio Fagundes ^{[1, 5, 6]} ; Pires, Flavio Oliveira ^{[1, 2]}

Affiliation

^[1] Univ Sao Paulo, Sch Arts Sci & Humanities, Exercise Psychophysiol Res Grp, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Human Movement Sci & Rehabil Program, Santos, SP - Brazil

^[3] Estacio Sa Univ UNESA, Resende - Brazil

^[4] Univ Kent, Sch Sport & Exercise Sci, Canterbury, Kent - England

^[5] Univ Porto, Fac Sport, Ctr Res Educ Innovat & Intervent Sport, Porto - Portugal

^[6] Univ Porto, Porto Biomech Lab LABIOMEP, Porto - Portugal

• Document type: Journal article
• Source: PSYCHOPHYSIOLOGY; v. 58, n. 6 MAR 2021.
• Web of Science Citations: 1

Abstract

Pain arising from exercise potentiates fatigue and impairs the performance of endurance exercise. We assessed neurophysiological and perceptual responses to endurance exercise performed under experimentally induced muscle pain by a model that separates muscle pain from muscle fatigue. After a series of pilot studies investigating different hypertonic saline volumes, 17 healthy males performed a preliminary VO2PEAK test before performing a familiarization of the cycling time-to-exhaustion exercise (80% of the peak power output in the VO2PEAK test). Participants, performed a baseline exercise session before the sessions with hypertonic and isotonic saline injections in the vastus lateralis of both legs, in a crossover and counterbalanced design. Neurophysiological and perceptual responses such as electroencephalography (EEG) in frontal, prefrontal, parietal, and motor cortex, electromyography (EMG) of the vastus lateralis and biceps femoris muscles, ratings of perceived exertion (RPE), pain sensation, and affective valence were measured at rest and during exercise. The hypertonic injection reduced the resting EEG alpha-beta ratio in the frontal and prefrontal cortex. When compared to exercise performed after the isotonic injection (430.5 +/- 152.6 s), hypertonic injection shortened the time-to-exhaustion (357.5 +/- 173.0 s), reduced the EMG of the assessed muscles, and increased the muscle co-contraction during exercise. The hypertonic injection also reduced the EEG alpha-beta ratio in the prefrontal and parietal cortex, increased RPE and pain sensation, and reduced affective valence during exercise. This proof-of-concept study showed that hypertonic injection-induced muscle pain reduced endurance performance, promoting centrally mediated alterations in motor command and cortical activation, as well as an interplay of perceptual responses. (AU)

• FAPESP's process: 16/16496-3 - Effects of carbohydrate mouth rinse on physical performance and psychophysiological responses in individuals mentally fatigued during VO2MAX test
• Grantee: Flávio de Oliveira Pires
• Support Opportunities: Regular Research Grants