Selection for feed efficiency elicits different postprandial plasma metabolite profiles in response to poor hygiene of housing conditions in growing pigs

Author(s)

Zem Fraga, Alicia ^{[1, 2]} ; Louveau, Isabelle ^[2] ; Campos, Paulo Henrique Reis Furtado ^[3] ; Hauschild, Luciano ^[1] ; Le Floc'h, Nathalie ^[2]

Affiliation

^[1] Sao Paulo State Univ, Sch Agr & Vet Sci, Dept Anim Sci, Jaboticabal, SP - Brazil

^[2] Inst Agro, INRAE, PEGASE, St Gilles - France

^[3] Univ Fed Vicosa, Dept Anim Sci, Vicosa, MG - Brazil

• Document type: Journal article
• Source: PLoS One; v. 16, n. 3 MAR 29 2021.
• Web of Science Citations: 1

Abstract

This study was conducted to compare postprandial plasma concentrations of insulin, energy-related metabolites, and amino acids measured after a 6-week challenge consisting of exposure to good or poor hygiene of housing conditions of 24 growing pigs divergently selected for low-RFI (LRFI) and high-RFI (HRFI). Blood indicators of immune responses were assessed from samples collected before 0 (W0), and 3 (W3), and 6 weeks (W6) after pigs transfer to their respective hygiene of housing conditions. Plasma haptoglobin concentrations and blood neutrophil granulocyte numbers were greater in poor than in good hygiene of housing conditions at W3. Plasma concentrations of total immunoglobulin G were greater (p = 0.04) in poor than in good hygiene of housing conditions at W6. At W6, pigs were fitted with an intravenous catheter for serial blood samplings. Low-RFI pigs had greater insulin (p < 0.001) and lower triglyceride (p = 0.04) average plasma concentrations than HRFI pigs in both conditions. In poor hygiene of housing conditions, the peaks of insulin and glucose were observed earlier and that of insulin was greater in LRFI than in HRFI pigs. Irrespective of genetic line, average plasma concentrations of histidine, isoleucine, leucine, methionine, threonine, valine, and alanine were greater in poor compared with good hygiene of housing conditions. Only HRFI pigs had greater lysine, asparagine, proline, and tyrosine plasma concentrations in poor than in good hygiene of housing conditions. Conversely, arginine, tryptophan, proline, and tyrosine plasma concentrations were lower only for LRFI pigs housed in poor hygiene conditions. Our results suggest that, contrary to HRFI, LRFI pigs increase or maintain their utilization of tryptophan, arginine, and lysine when housed in poor hygiene conditions. This indicates that this difference may contribute to the better capacity of LRFI to cope with poor hygiene of housing conditions. (AU)

• FAPESP's process: 18/11807-6 - Housing hygiene conditions affect postprandial profiles of amino acids and metabolites in pigs selected for low and high residual feed intake
• Grantee: Alícia Zem Fraga
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 18/15559-7 - Precision nutrition for sanitary challenged pigs reared in hot climate areas
• Grantee: Luciano Hauschild
• Support Opportunities: Research Grants - Young Investigators Grants - Phase 2