SARS-CoV-2 reinfection caused by the P.1 lineage in Araraquara city, Sao Paulo State, Brazil

Author(s):Show less -

Romano, Camila Malta ^{[1, 2]} ; Felix, Alvina Clara ^[2] ; de Paula, Anderson Vicente ^[2] ; de Jesus, Jaqueline Goes ^[2] ; Andrade, Pamela S. ^[2] ; Candido, Darlan ^{[3, 2]} ; de Oliveira, Franciane M. ^[2] ; Ribeiro, Andreia C. ^[4] ; da Silva, Francini C. ^[4] ; Inemami, Marta ^[4] ; Costa, Angela Aparecida ^[4] ; Leal, Cibele O. D. ^[2] ; Figueiredo, Walter Manso ^[4] ; Pannuti, Claudio Sergio ^[2] ; de Souza, William M. ^[5] ; Faria, Nuno Rodrigues ^{[6, 7]} ; Sabino, Ester Cerdeira ^{[6, 2]}

Affiliation

^[1] Univ Sao Paulo, Hosp Clin, Fac Med, Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Inst Med Trop Sao Paulo, Av Dr Eneas Carvalho Aguiar 470, BR-05403000 Sao Paulo, SP - Brazil

^[3] Univ Oxford, Dept Zool, Oxford - England

^[4] Univ Sao Paulo, Serv Especial Saude Araraquara, Sao Paulo, SP - Brazil

^[5] Univ Sao Paulo, Fac Med Ribeirao Preto, Ctr Pesquisa Virol, Ribeirao Preto, SP - Brazil

^[6] Univ Sao Paulo, Fac Med, Dept Molestias Infecciosas & Parasitarias, Sao Paulo, SP - Brazil

^[7] Imperial Coll London, MRC Ctr Global Infect Dis Anal, London - England

• Document type: Journal article
• Source: Revista do Instituto de Medicina Tropical de São Paulo; v. 63, 2021.
• Web of Science Citations: 8

Abstract

ABSTRACT Reinfection by the severe acute respiratory syndrome coronavirus type 2 (SARS-COV-2) has been reported in many countries, suggesting that the virus may continue to circulate among humans despite the possibility of local herd immunity due to massive previous infections. The emergence of variants of concern (VOC) that are more transmissible than the previous circulating ones has raised particular concerns on the vaccines effectiveness and reinfection rates. The P.1 lineage was first identified in December 2020 in Manaus city and is now globally spread. We report the first case of reinfection of SARS-CoV-2 caused by the P.1 variant outside of Manaus. The potential of these new variants to escape naturally and vaccine- induced immunity highlights the need for a global vigilance. (AU)

• FAPESP's process: 17/13981-0 - Characterization, genomics and diagnostic of viruses with importance for public health in Brazil by high throughput sequencing
• Grantee: William Marciel de Souza
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/03859-9 - Clinical, serological and virological characteristics of Dengue virus serotype 2 (DENV-2) infection in a cohort previously exposed to serotype 1
• Grantee: Camila Malta Romano
• Support Opportunities: Regular Research Grants
• FAPESP's process: 19/24251-9 - Multi-omic approaches for the study of Chikungunya disease
• Grantee: William Marciel de Souza
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 18/14389-0 - Brazil-UK Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE)
• Grantee: Ester Cerdeira Sabino
• Support Opportunities: Research Projects - Thematic Grants