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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of the Andean Geography and Climate on the Specialized Metabolism of Its Vegetation: The Subtribe Espeletiinae (Asteraceae) as a Case Example

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Author(s):
Padilla-Gonzalez, Guillermo E. [1, 2] ; Diazgranados, Mauricio [3] ; Da Costa, Fernando B. [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Lab Pharmacognosy, AsterBioChem Res Team, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Royal Bot Gardens, Jodrell Lab, Kew Rd, London TW9 3AB - England
[3] Royal Bot Gardens, Millennium Seed Bank, Haywards Heath RH17 6TN, W Sussex - England
Total Affiliations: 3
Document type: Journal article
Source: METABOLITES; v. 11, n. 4 APR 2021.
Web of Science Citations: 0
Abstract

The Andean mountains are `center stage' to some of the most spectacular examples of plant diversifications, where geographic isolation and past climatic fluctuations have played a major role. However, the influence of Andean geography and climate as drivers of metabolic variation in Andean plants is poorly elucidated. Here, we studied the influence of those factors on the metabolome of the subtribe Espeletiinae (Asteraceae) using liquid chromatography coupled to high-resolution mass spectrometry data of over two hundred samples from multiple locations. Our results demonstrate that metabolic profiles can discriminate Espeletiinae taxa at different geographic scales, revealing inter- and intraspecific metabolic variations: at the country level, segregation between Colombian and Venezuelan taxa was observed; regionally, between paramo massifs; and locally, between paramo complexes. Metabolic differences in Espeletiinae were mainly explained by geographic isolation, although differences in taxonomic genera, temperature, and elevation, were also important. Furthermore, we found that different species inhabiting the same paramo complex showed stronger chemical similarities than the same species at different locations, corroborating that geographic isolation represents the main driver of metabolic change in Espeletiinae. The current study serves as a starting point to fill in the gaps in how Andean geography and climate have shaped the metabolism of its vegetation and reveal the potential of untargeted metabolomics to study the environmental physiology of plants. (AU)

FAPESP's process: 16/21183-4 - Metabolic fingerprinting and biosynthesis of sesquiterpene lactones in Smallanthus sonchifolius and Espeletia (Asteraceae): a metabolomic and transcriptomic approach
Grantee:Guillermo Federico Padilla Gonzalez
Support Opportunities: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 14/17702-0 - Metabolomics and evolution of chemical characters in the subtribe Espeletiinae (Asteraceae)
Grantee:Guillermo Federico Padilla Gonzalez
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 14/26866-7 - Metabolomics, enzymatic targets and in silico tools in the search of bioactive compounds from plants
Grantee:Fernando Batista da Costa
Support Opportunities: Regular Research Grants
FAPESP's process: 10/51454-3 - Morphoanatomical, metabolomic and molecular studies as subsidies to the systematic of Asteraceae species and access to their pharmacological potential
Grantee:Beatriz Appezzato da Glória
Support Opportunities: Research Projects - Thematic Grants