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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Reliability and validity of six-minute step test in patients with heart failure

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Marinho, R. S. [1] ; Jurgensen, S. P. [2] ; Arcuri, J. F. [2] ; Goulart, C. L. [2] ; dos Santos, P. B. [2] ; Roscani, M. G. [3] ; Mendes, R. G. [2] ; de Oliveira, C. R. [3] ; Caruso, F. R. [2] ; Borghi-Silva, A. [2, 1]
Total Authors: 10
[1] Univ Sao Paulo, Programa Posgrad Interunidades Bioengn, Sao Carlos, SP - Brazil
[2] Univ Fed Sao Carlos, Dept Fisioterapia, Sao Carlos, SP - Brazil
[3] Univ Fed Sao Carlos, Dept Med, Sao Carlos, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Brazilian Journal of Medical and Biological Research; v. 54, n. 10 2021.
Web of Science Citations: 0

Exercise intolerance is the hallmark consequence of advanced chronic heart failure (HF). The six-minute step test (6MST) has been considered an option for the six-minute walk test because it is safe, inexpensive, and can be applied in small places. However, its reliability and concurrent validity has still not been investigated in participants with HF with reduced ejection fraction (HFrEF). Clinically stable HFrEF participants were included. Reliability and error measurement were calculated by comparing the first with the second 6MST result. Forty-eight hours after participants underwent the 6MST, they were invited to perform a cardiopulmonary exercise test (CPET) on a cycle ergometer. Concurrent validity was assessed by correlation between number of steps and peak oxygen uptake (V̇O2 peak) at CPET. Twenty-seven participants with HFrEF (60±8 years old and left ventricle ejection fraction of 41±6%) undertook a mean of 94±30 steps in the 6MST. Intra-rater reliability was excellent for 6MST (ICC=0.9), with mean error of 4.85 steps and superior and inferior limits of agreement of 30.6 and -20.9 steps, respectively. In addition, strong correlations between number of steps and CPET workload (r=0.76, P<0.01) and peak V̇O2 (r=0.71, P<0.01) were observed. From simple linear regression the following predictive equations were obtained with 6MST results: V̇O2 peak (mL/min) = 350.22 + (7.333 × number of steps), with R2=0.51, and peak workload (W) = 4.044 + (0.772 × number of steps), with R2=0.58. The 6MST was a reliable and valid tool to assess functional capacity in HFrEF participants and may moderately predict peak workload and oxygen uptake of a CPET. (AU)

FAPESP's process: 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach
Grantee:Audrey Borghi e Silva
Support Opportunities: Research Projects - Thematic Grants