Conceptual Framework for Insomnia: A Cognitive Model in Practice

Author(s)

Vaziri, Zahra ^{[1, 2]} ; Nami, Mohammad ^{[3, 4, 5, 6, 7]} ; Leite, Joao Pereira ^[1] ; Delbem, Alexandre Claudio Botazzo ^{[2, 8]} ; Hyppolito, Miguel Angelo ^[9] ; Ghodratitoostani, Iman ^{[2, 8]}

Affiliation

^[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Neurosci & Behav Sci, Ribeirao Preto - Brazil

^[2] Univ Sao Paulo, Inst Math & Comp Sci, Neurocognit Engn Lab NEL, Sao Carlos - Brazil

^[3] Inst Invest Cient Serv Alta Tecnol INDICASAT AIP, Neurosci Ctr, Panama City - Panama

^[4] Shiraz Univ Med Sci, Sch Adv Med Sci & Technol, Dept Neurosci, Shiraz - Iran

^[5] Iranian Neurosci Soc Fars Chapter, Dana Brain Hlth Inst, Shiraz - Iran

^[6] Senses Cultural Fdn, Acad Hlth, Sacramento, CA - USA

^[7] Inst Cognit Sci Studies ICSS, Dept Cognit Neurosci, Pardis - Iran

^[8] Univ Sao Paulo, Inst Math & Comp Sci, Reconfigurable Comp Lab, Sao Carlos - Brazil

^[9] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Ophthalmol Otorhinolaryngol Head & Neck Surg, Ribeirao Preto - Brazil

• Document type: Journal article
• Source: FRONTIERS IN NEUROSCIENCE; v. 15, JUL 22 2021.
• Web of Science Citations: 0

Abstract

Insomnia is a widespread neuropsychological sleep-related disorder known to result in various predicaments including cognitive impairments, emotional distress, negative thoughts, and perceived sleep insufficiency besides affecting the incidence and aggravation of other medical disorders. Despite the available insomnia-related theoretical cognitive models, clinical studies, and related guidelines, an evidence-based conceptual framework for a personalized approach to insomnia seems to be lacking. This study proposes a conceptual cognitive framework (CCF) providing insight into cognitive mechanisms involved in the predisposition, precipitation, and perpetuation of insomnia and consequent cognitive deficits. The current CCF for insomnia relies on evaluative conditional learning and appraisal which generates negative valence (emotional value) and arousal (cognitive value). Even with the limitations of this study, the suggested methodology is well-defined, reproducible, and accessible can help foster future high-quality clinical databases. During clinical insomnia but not the neutral one, negative mood (trait-anxiety) causes cognitive impairments only if mediating with a distorted perception of insomnia (Ind-1 = 0.161, 95% CI 0.040-0.311). Further real-life testing of the CCF is intended to formulate a meticulous, decision-supporting platform for clinical interventions. Furthermore, the suggested methodology is expected to offer a reliable platform for CCF-development in other cognitive impairments and support the causal clinical data models. It may also improve our knowledge of psychological disturbances and complex comorbidities to help design rehabilitation interventions and comprehensive frameworks in line with the ``preventive medicine `` policies. (AU)

• FAPESP's process: 13/07375-0 - CeMEAI - Center for Mathematical Sciences Applied to Industry
• Grantee: Francisco Louzada Neto
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC