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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synergic effects of ultrasound and laser therapies on mesentery for management of obesity and diabetes in rats

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Author(s):
Paolillo, Fernanda Rossi [1] ; Teofilo Borges Campos, Thays Yara [2] ; Alvarez, Carolina [2] ; Sene-Fiorese, Marcela [3] ; Bagnato, Vanderlei Salvador [2] ; Garcia Oliveira Duarte, Ana Claudia [3] ; Parizotto, Nivaldo Antonio [4, 5]
Total Authors: 7
Affiliation:
[1] State Univ Minas Gerais UEMG, Grp Technol Appl Hlth & Motr Sci, R Colorado, 700 Bairro Sao Francisco, BR-37902092 Passos, MG - Brazil
[2] Univ Sao Paulo, Sao Carlos Inst Phys IFSC, Opt Grp, Sao Carlos - Brazil
[3] Fed Univ Sao Carlos UFSCar, Dept Phys Educ & Human Motr, Sao Carlos - Brazil
[4] Fed Univ Sao Carlos UFSCar, Electrothermophototherapy Lab, Dept Phys Therapy, Sao Carlos - Brazil
[5] Fed Univ Paraiba UFPB, Dept Phys Therapy, Joao Pessoa, Paraiba - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Journal of Biophotonics; v. 14, n. 11 AUG 2021.
Web of Science Citations: 0
Abstract

Nowadays, the mesentery as a new organ was discovered. Mesenteric events may play an important role in the pathophysiology of several diseases. The aim of our study was investigate the synergic effects of ultrasound (US) and laser therapies on mesentery in obese-hyperglycemic rats. The 25 male Wistar rats were randomized into five groups. Obese nondiabetic (OND) group: obese rats without diabetes and no treatment conditions; SHAM group: obese-hyperglycemic rats treated with placebo; US group: obese-hyperglycemic rats treated with US; LASER group: obese-hyperglycemic rats treated with laser and; US+LASER group: obese-hyperglycemic rats treated with US plus laser. An animal model of type 2 diabetes based on a hyperlipidemic diet combined with a low dose of streptozotocin was used in this study. Body mass and biochemical measurements were performed. GOT and GPT level showed a significant reduction in the treated groups than SHAM. The total cholesterol, triglycerides and very low-density lipoprotein (VLDL) levels showed significantly lower values for the US+LASER group. There was also reduced risk of cardiovascular diseases evidenced by Castelli index in the treated groups than SHAM. This study showed that the US and laser treatment on mesentery resulted to an improvement in biochemical measurements of the obese-hyperglycemic rats, especially the total cholesterol, triglycerides and VLDL levels. (AU)

FAPESP's process: 13/14001-9 - FLUORESCENCE SPECTROSCOPY OF TOOTH IN OVARIECTOMIZED RATS FOR OSTEOPOROSIS DIAGNOSIS
Grantee:Fernanda Rossi Paolillo
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 13/07276-1 - CEPOF - Optics and Photonic Research Center
Grantee:Vanderlei Salvador Bagnato
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC