| Full text | |
| Author(s): |
Acevedo, Luisa Alegria
[1]
;
Campos, Leticia Antonelo
[1]
;
Dechandt, Iolanda Cristina
[2]
;
Alegria, Gustavo
[3]
;
Siqueira, Renato Luiz
[4]
;
Zanotto, Edgar Dutra
[4]
;
Serbena, Francisco Carlos
[2]
;
Santos, Fabio Andre
[1]
Total Authors: 8
|
| Affiliation: | [1] Univ Estadual Ponta Grossa, Sch Dent, State Univ Ponta Grossa, Ponta Grossa, PR - Brazil
[2] Univ Estadual Ponta Grossa, Sch Phys, State Univ Ponta Grossa, Ponta Grossa, PR - Brazil
[3] Univ Valle, Dept Dent, Santiago De Cali, Valle Del Cauca - Colombia
[4] Univ Fed Sao Carlos, Dept Mat Engn, UFSCar, Sao Carlos, SP - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS; v. 110, n. 3 SEP 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Dentin hypersensitivity (DH) is characterized by pain caused by an external stimulus on exposed dentin. Different therapeutic approaches have been proposed to mitigate this problem; however, none of them provide permanent pain relief. In this study, we synthesized and characterized experimental bioactive glasses containing 3.07 mol% SrO or 3.36 mol% K2O (both equivalent to 5 wt% in the glass), and evaluated their effect on dentin permeability to verify their potential to treat DH. The experimental materials were characterized by field-emission scanning electron microscopy, Fourier transform infrared spectroscopy, micro-Raman spectroscopy, and X-ray diffraction to confirm the respective structures and chemical compositions. The reduction in the hydraulic conductance of dentin was evaluated at the three stages: minimum permeability; maximum permeability (24% ethylenediaminetetraacetic acid {[}EDTA] treatment); and final dentin permeability after treatment with the bioactive glasses. They all promoted a reduction in dentin permeability, with a significant difference for each sample and posttreatment group. Also, a significant reduction in dentin permeability was observed even after a simulated toothbrushing test, demonstrating effective action of these materials against DH. Besides, incorporating 3.07 mol% SrO was a positive factor. Therefore, strontium's desensitizing and re-mineralizing properties can be further exploited in bioactive glasses to promote a synergistic effect to treat DH. (AU) | |
| FAPESP's process: | 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass |
| Grantee: | Edgar Dutra Zanotto |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |