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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Vitamin E: A potential preventive approach against dental erosion-an in vitro short-term erosive study

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Rios, Daniela [1] ; Boteon, Ana Paula [1] ; Leone, Camilla Cristina Lira Di [1] ; Castelluccio, Tainara Tonon [1] ; Mendonca, Fernanda Lyrio [1] ; Ionta, Franciny Querobim [2] ; Buzalaf, Marilia Afonso Rabelo [3] ; Carvalho, Thiago Saads [4]
Total Authors: 8
[1] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Publ Hlth, Bauru, SP - Brazil
[2] Univ Marilia, Dept Pediat Dent, Marilia, SP - Brazil
[3] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Bauru, SP - Brazil
[4] Univ Bern, Dept Prevent Restorat & Pediat Dent, Bern - Switzerland
Total Affiliations: 4
Document type: Journal article
Source: Journal of Dentistry; v. 113, OCT 2021.
Web of Science Citations: 0

Objectives: This study evaluated the in vitro effect of different components of palm oil on enamel in a short-term erosive challenge. Methods: The acquired enamel pellicle (AEP) was previously formed in situ for 2 h. Subsequently, the bovine enamel blocks were treated in vitro according to following solutions: G1-palm oil; G2-85% tocotrienol solution; G3-oily vitamin E; G4-oily vitamin A; G5-deionized water (negative control); G6-stannous-containing solution (Elmex (R) Erosion Protection Dental Rinse) (positive control). After application of the treatment solutions (500 mu l, 30 s), the blocks were immersed in 0.5% citric acid (pH 2.4) during 30 s (initial erosion). The response variable was the percentage of surface hardness loss. Data were analyzed by one-way ANOVA and Fisher's Test (p < 0.05). Results: The positive control (G6), palm oil (G1) and oily vitamin E (G3) groups presented the lowest percentage of surface hardness loss, and were statistically different from the negative group (G5) (p < 0.05), and no differences were found between these three groups. The 85% tocotrienol solution (G2) and oily vitamin A groups (G4) were not different to the negative control group. Conclusions: Stannous-containing positive control (Elmex (R) Erosion Protection), palm oil and oily Vitamin E were able to protect enamel against the erosive challenge performed in this in vitro study. In addition, vitamin E is probably the key ingredient of palm oil responsible for preventing enamel erosion. Clinical significance: Vitamin E presented similar preventive effect to a commercial mouthwash stannouscontaining solution (Elmex (R) Erosion Protection) against initial erosion and, it can be considered as a promising natural alternative for the formulations of solutions aiming to prevent erosive tooth wear. (AU)

FAPESP's process: 18/19671-6 - Evaluation of components of palm oil possibly responsible for its protective effect against erosion
Grantee:Tainara Tonon Castelluccio
Support Opportunities: Scholarships in Brazil - Scientific Initiation