2-Nitro- and 4-fluorocinnamaldehyde based receptors as naked-eye chemosensors to potential molecular keypad lock

Author(s):Show less -

Islam, Muhammad ^[1] ; Shafiq, Zahid ^[1] ; Mabood, Fazal ^{[2, 3]} ; Shah, Hakikulla H. ^[2] ; Singh, Vandita ^[4] ; Khalid, Muhammad ^[5] ; de Alcantara Morais, Sara Figueiredo ^[6] ; Carmo Braga, Ataualpa Albert ^[6] ; Khan, Muhammad Usman ^[7] ; Hussain, Javid ^[2] ; Al-Harrasi, Ahmed ^[2] ; Marraiki, Najat ^[8] ; Zaghloul, Nouf S. S. ^[9]

Affiliation

^[1] Bahauddin Zakariya Univ, Inst Chem Sci, Multan 60800 - Pakistan

^[2] Univ Nizwa, Nat & Med Sci Res Ctr, POB 33, Nizwa 616 - Oman

^[3] Univ Swat, Inst Chem Sci, Swat - Pakistan

^[4] ASharqiyah Univ, Coll Appl & Hlth Sci, Dept Food Sci & Human Nutr, POB 42, Ibra - Oman

^[5] Khwaja Fareed Univ Engn & Informat Technol, Dept Chem, Rahim Yar Khan 64200 - Pakistan

^[6] Univ Sao Paulo, Inst Quim, Dept Quim Fundamental, Ave Prof LineuPrestes 748, BR-05508000 Sao Paulo - Brazil

^[7] Univ Okara, Dept Chem, Okara 56300 - Pakistan

^[8] King Saud Univ, Coll Sci, Dept Bot & Microbiol, PO 2455, Riyadh 11451 - Saudi Arabia

^[9] Univ Bristol, Bristol Ctr Funct Nanomat, HH Wills Phys Lab, Tyndall Ave, Bristol BS8 1FD, Avon - England

• Document type: Journal article
• Source: SCIENTIFIC REPORTS; v. 11, n. 1 OCT 21 2021.
• Web of Science Citations: 0

Abstract

New-generation chemosensors desire small organic molecules that are easy to synthesise and cost-effective. As a new interdisciplinary area of research, the integration of these chemosensors into keypad locks or other advanced communication protocols is becoming increasingly popular. Our lab has developed new chemosensor probes that contain 2-nitro- (1-3) and 4-fluoro-cinnamaldehyde (4-6) and applied them to the anion recognition and sensing process. Probes 1-6 are colorimetric sensors for naked-eye detection of AcO-/CN-/F-, while probes 4-6 could differentiate between F- and AcO-/CN- anions in acetonitrile. Using the density functional theory (DFT), it was found that probes 1-6 acted as effective chemosensors. By using Probe 5 as a chemosensor, we explored colorimetric recognition of multiple anions in more detail. Probe 5 was tested in combination with a combinatorial approach to demonstrate pattern-generation capability and its ability to distinguish among chemical inputs based on concentration. After pattern discrimination using principal component analysis (PCA), we examined anion selectivity using DFT computation. In our study, probe 5 demonstrates excellent performance as a chemosensor and shows promise as a future molecular-level keypad lock system. (AU)

• FAPESP's process: 11/07895-8 - Theoretical study of the Heck-Matsuda reactions
• Grantee: Ataualpa Albert Carmo Braga
• Support type: Scholarships in Brazil - Post-Doctorate
• FAPESP's process: 15/01491-3 - Theoretical study of cross-coupling reactions: homogeneous and heterogeneous catalysis
• Grantee: Ataualpa Albert Carmo Braga
• Support type: Regular Research Grants
• FAPESP's process: 14/25770-6 - New frontiers in cross-coupling reactions promoted by palladium: combining enantioselective catalysis, C-H activations, new materials and in flux reactions aiming at high efficiency and sustainability in synthetic processes
• Grantee: Carlos Roque Duarte Correia
• Support type: Research Projects - Thematic Grants