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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Stability of SARS-CoV-2 and other airborne viruses under different stress conditions

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Author(s):
Fumagalli, Marcilio Jorge [1] ; Capato, Carlos Fabiano [1] ; de Castro-Jorge, Luiza Antunes [1] ; de Souza, William Marciel [1] ; Arruda, Eurico [1] ; Figueiredo, Luiz Tadeu Moraes [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Virol Res Ctr, Av Bandeirantes 3900, BR-14049090 Ribeirao Preto - Brazil
Total Affiliations: 1
Document type: Journal article
Source: ARCHIVES OF VIROLOGY; v. 167, n. 1 NOV 2021.
Web of Science Citations: 0
Abstract

Viral stability under stress conditions may directly affect viral dissemination, seasonality, and pathogenesis. We exposed airborne viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mumps virus, coxsackievirus B5, human rhinovirus A16, and respiratory syncytial virus, to different temperatures, UV light exposure time, pH values, and osmotic pressures and measured the remaining viral infectivity. Reduced thermal stability was observed for coxsackievirus B5 at 45 degrees C, while SARS-CoV-2 demonstrated residual infectivity at 55 degrees C. UV light exposure was an efficient means of viral inactivation but was less efficient for non-enveloped viruses. Rhinovirus A16 and respiratory syncytial virus demonstrated extreme sensitivity to acid conditions, while SARS-CoV-2, rhinovirus A16, and respiratory syncytial virus were unstable in an alkaline environment. The information obtained in this study will be useful for the development of viral inactivation methods and may be correlated with epidemiological and seasonal viral characteristics. (AU)

FAPESP's process: 18/09383-3 - Study about Flavivirus epitopes with medical importance in Brazil and its antibodies
Grantee:Marcilio Jorge Fumagalli
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 19/26119-0 - Emerging and re-emerging viruses: biology, pathogenesis and prospection
Grantee:Eurico de Arruda Neto
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 19/27333-6 - Pathophysiology and diagnosis of arthritogenic alphavirus infections
Grantee:Luiz Tadeu Moraes Figueiredo
Support Opportunities: Regular Research Grants