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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Poor Sleep quality and health-related quality of life impact in adolescents with and without chronic immunosuppressive conditions during COVID-19 quarantine

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Helito, Alberto C. [1] ; Lindoso, Livia [1] ; Sieczkowska, Sofia M. [1] ; Astley, Camilla [1] ; Queiroz, Ligia B. [1] ; Rose, Natalia [1] ; Santos, Claudia Renata P. [1] ; Bolzan, Thalis [1] ; Peralta, Rita Maria I. A. [1] ; Franco, Ruth R. [1] ; Cominato, Louise [1] ; Pereira, Rosa Maria R. [1] ; Tannuri, Uenis [1] ; Campos, Lucia Maria A. [1] ; Lourenco, Benito [1] ; Toma, Ricardo K. [1] ; Medeiros, Karina [1] ; Watanabe, Andreia [1] ; Grangeiro, Patricia Moreno [1] ; Farhat, Sylvia C. [1] ; Casella, Caio B. [1] ; Polanczyk, V, Guilherme ; Gualano, Bruno [2] ; Silva, Clovis A. [2] ; Study, HC-FMUSP Adolescent COVID-19
Total Authors: 25
Affiliation:
[1] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Sao Paulo, SP - Brazil
[2] Polanczyk, Guilherme, V, Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Clinics; v. 76, 2021.
Web of Science Citations: 1
Abstract

OBJECTIVE: To assess the possible factors that influence sleep quality in adolescents with and without chronic immunosuppressive conditions quarantined during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: This cross-sectional study included 305 adolescents with chronic immunocompromised conditions and 82 healthy adolescents. Online surveys were completed, which included questions on socio-demographic data and self-rated healthcare routine during COVID-19 quarantine and the following validated questionnaires: the Pittsburgh Sleep Quality Index (PSQI), Pediatric Quality of Life Inventory 4.0 (PedsQL4.0), and Pediatric Outcome Data Collection Instrument (PODCI). RESULTS: The median current age {[}14 (10-18) vs. 15 (10-18) years, p=0.847] and frequency of female sex (62% vs. 58%, p=0.571) were similar in adolescents with chronic conditions compared with healthy adolescents. The frequency of poor sleep quality was similar in both groups (38% vs. 48%, p=0.118). Logistic regression analysis, including both healthy adolescents and adolescents with chronic conditions (n=387), demonstrated that self-reported increase in screen time (odds ratio {[}OR] 3.0; 95% confidence interval {[}CI] 1.3-6.8; p=0.008) and intrafamilial violence report (OR 2.1; 95% CI 1.2-3.5; p=0.008) were independently associated with poor sleep quality in these adolescents. However, the PODCI global function score was associated with a lower OR for poor sleep quality (OR 0.97; 95% CI 0.94-0.99; p=0.001). Further logistic regression, including only adolescents with chronic conditions (n=305), demonstrated that self-reported increase in screen time (OR 3.1; 95% CI 1.4-6.8; p=0.006) and intrafamilial violence report (OR 2.0; 95% CI 1.2-3.4; p=0.011) remained independently associated with poor quality of sleep, whereas a lower PODCI global function score was associated with a lower OR for sleep quality (OR 0.96; 95% CI 0.94-0.98; p < 0.001). CONCLUSION: Self-reported increases in screen time and intrafamilial violence report impacted sleep quality in both healthy adolescents and those with chronic conditions. Decreased health-related quality of life was observed in adolescents with poor sleep quality. (AU)

FAPESP's process: 15/03756-4 - Assessment of relevance of blood levels of drugs in the monitoring rheumatic autoimmune diseases: safety, effectiveness and adherence to therapy
Grantee:Eloisa Silva Dutra de Oliveira Bonfá
Support Opportunities: Research Projects - Thematic Grants