| Full text | |
| Author(s): Show less - |
Lyra, Mariana L.
[1]
;
Monteiro, Juliane P. C.
[1]
;
Rancilhac, Lois
[2]
;
Irisarri, Iker
[3]
;
Kuenzel, Sven
[4]
;
Sanchez, Eugenia
[2]
;
Condez, Thais H.
[5]
;
Rojas-Padilla, Omar
[6]
;
Sole, Mirco
[7]
;
Toledo, Luis Felipe
[8]
;
Haddad, Celio F. B.
[1]
;
Vences, Miguel
[2]
Total Authors: 12
|
| Affiliation: | [1] Univ Estadual Paulista UNESP, Dept Biodiversidade, Inst Biociencias, Campus Rio Claro, Ave 24A, N 1515, BR-13506900 Rio Claro, SP - Brazil
[2] Tech Univ Carolo Wilhelmina Braunschweig, Zool Inst, D-38106 Braunschweig - Germany
[3] Univ Goettingen, Dept Appl Bioinformat, Inst Microbiol & Genet, Goldschmidtstr 1, D-37077 Gottingen - Germany
[4] Max Planck Inst Evolutionary Biol, D-24306 Plon - Germany
[5] Univ Estado Minas Gerais UEMG, Unidade Passos, Ave Juca Stockler 1130, BR-37900106 Passos, MG - Brazil
[6] Pontificia Univ Catolica Rio Grande do Sul, Lab Sistemat Vertebrados, Av Ipiranga 6681, BR-90619900 Porto Alegre, RS - Brazil
[7] Univ Estadual Santa Cruz, Dept Ciencias Biol, BR-45662900 Ilheus, BA - Brazil
[8] Univ Estadual Campinas, Inst Biol, Dept Biol Anim, Lab Hist Nat Anfibios Brasileiros LaHNAB, BR-13083862 Campinas, SP - Brazil
Total Affiliations: 8
|
| Document type: | Journal article |
| Source: | TOXINS; v. 13, n. 11 NOV 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
The genus Brachycephalus is a fascinating group of miniaturized anurans from the Brazilian Atlantic Forest, comprising the conspicuous, brightly colored pumpkin-toadlets and the cryptic flea-toads. Pumpkin-toadlets are known to contain tetrodotoxins and therefore, their bright colors may perform an aposematic function. Previous studies based on a limited number of mitochondrial and nuclear-encoded markers supported the existence of two clades containing species of pumpkin-toadlet phenotype, but deep nodes remained largely unresolved or conflicting between data sets. We use new RNAseq data of 17 individuals from nine Brachycephalus species to infer their evolutionary relationships from a phylogenomic perspective. Analyses of almost 5300 nuclear-encoded ortholog protein-coding genes and full mitochondrial genomes confirmed the existence of two separate pumpkin-toadlet clades, suggesting the convergent evolution (or multiple reversals) of the bufoniform morphology, conspicuous coloration, and probably toxicity. In addition, the study of the mitochondrial gene order revealed that three species (B. hermogenesi, B. pitanga, and B. rotenbergae) display translocations of different tRNAs (NCY and CYA) from the WANCY tRNA cluster to a position between the genes ATP6 and COIII, showing a new mitochondrial gene order arrangement for vertebrates. The newly clarified phylogeny suggests that Brachycephalus has the potential to become a promising model taxon to understand the evolution of coloration, body plan and toxicity. Given that toxicity information is available for only few species of Brachycephalus, without data for any flea-toad species, we also emphasize the need for a wider screening of toxicity across species, together with more in-depth functional and ecological study of their phenotypes. (AU) | |
| FAPESP's process: | 17/26281-7 - Taxonomy and evolution in the genus Brachycephalus Fitzinger, 1826 (Anura: Brachycephalidae) |
| Grantee: | Thais Helena Condez |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 14/50342-8 - Amphibians of Lagamar Mosaic protected areas: diversity, conservation and perspectives |
| Grantee: | Célio Fernando Baptista Haddad |
| Support Opportunities: | Research Grants - Research Partnership for Technological Innovation - PITE |
| FAPESP's process: | 18/09691-0 - Evolutionary history of the Brachycephalus pernix group (Anura: Brachycephalidae) |
| Grantee: | Juliane Petry de Carli Monteiro |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 19/18335-5 - Passive air transportation of an amphibian lethal pathogen in high elevation sites: practical applications for protected areas conservation in the State of São Paulo |
| Grantee: | Luis Felipe de Toledo Ramos Pereira |
| Support Opportunities: | BIOTA-FAPESP Program - Regular Research Grants |
| FAPESP's process: | 16/25358-3 - The chytrid fungus: from its origins to its consequences |
| Grantee: | Luis Felipe de Toledo Ramos Pereira |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 13/50741-7 - Diversity and conservation of Brazilian amphibians |
| Grantee: | Célio Fernando Baptista Haddad |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |