| Full text | |
| Author(s): Show less - |
Meldal, Birgit H. M.
[1]
;
Perfetto, Livia
[1, 2]
;
Combe, Colin
[3]
;
Lubiana, Tiago
[4]
;
Cavalcante, Joao Vitor Ferreira
[5]
;
Bye-A-Jee, Hema
[1]
;
Waagmeester, Andra
[6]
;
Del-Toro, Noemi
[1]
;
Shrivastava, Anjali
[1]
;
Barrera, Elisabeth
[1]
;
Wong, Edith
[7]
;
Mlecnik, Bernhard
[8, 9, 10, 11]
;
Bindea, Gabriela
[1]
;
Panneerselvam, Kalpana
[1]
;
Willighagen, Egon
[12]
;
Rappsilber, Juri
[3, 13]
;
Porras, Pablo
[1]
;
Hermjakob, Henning
[1]
;
Orchard, Sandra
[1]
Total Authors: 19
|
| Affiliation: Show less - | [1] European Bioinformat Inst EMBL EBI, European Mol Biol Lab, Wellcome Genome Campus, Cambridge CB10 1SD - England
[2] Fdn Human Technopole, I-20157 Milan - Italy
[3] Univ Edinburgh, Wellcome Ctr Cell Biol, Edinburgh EH9 3BF, Midlothian - Scotland
[4] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Clin & Toxicol Anal, Av Prof Lineu Prestes 580, BR-05508000 Sao Paulo, SP - Brazil
[5] Univ Fed Rio Grande do Norte, Digital Metropolis Inst, Bioinformat Multidisciplinary Environm BioME, Av Odilon Gomes de Lima 1722, BR-59078400 Natal, RN - Brazil
[6] Micelio, Veltwijcklaan 305, B-2180 Ekeren - Belgium
[7] Stanford Univ, Sch Med, Dept Genet, Palo Alto, CA 94304 - USA
[8] INSERM, Lab Integrat Canc Immunol, F-75006 Paris - France
[9] Equipe Labellisee Ligue Canc, F-75006 Paris - France
[10] Univ Paris, Sorbonne Univ, Ctr Rech Cordeliers, F-75006 Paris - France
[11] Inovarion, F-75005 Paris - France
[12] Maastricht Univ, NUTRIM, Dept Bioinformat BiGCaT, Univ Singel 50, NL-6229 ER Maastricht - Netherlands
[13] Tech Univ Berlin, Bioanalyt, Inst Biotechnol, D-13355 Berlin - Germany
Total Affiliations: 13
|
| Document type: | Journal article |
| Source: | Nucleic Acids Research; v. 50, n. D1, p. D578-D586, JAN 7 2022. |
| Web of Science Citations: | 3 |
| Abstract | |
The Complex Portal (www.ebi.ac.uk/complexportal) is a manually curated, encyclopaedic database of macromolecular complexes with known function from a range of model organisms. It summarizes complex composition, topology and function along with links to a large range of domain-specific resources (i.e. wwPDB, EMDB and Reactome). Since the last update in 2019, we have produced a first draft complexome for Escherichia coli, maintained and updated that of Saccharomyces cerevisiae, added over 40 coronavirus complexes and increased the human complexome to over 1100 complexes that include approximately 200 complexes that act as targets for viral proteins or are part of the immune system. The display of protein features in ComplexViewer has been improved and the participant table is now colour-coordinated with the nodes in ComplexViewer. Community collaboration has expanded, for example by contributing to an analysis of putative transcription cofactors and providing data accessible to semantic web tools through Wikidata which is now populated with manually curated Complex Portal content through a new bot. Our data license is now CC0 to encourage data reuse. Users are encouraged to get in touch, provide us with feedback and send curation requests through the `Support' link. (AU) | |
| FAPESP's process: | 19/26284-1 - Building a biological knowledge graph via Wikidata with a focus on the Human Cell Atlas |
| Grantee: | Tiago Lubiana Alves |
| Support Opportunities: | Scholarships in Brazil - Doctorate |