Applications of Plasma-Activated Water in Dentistry: A Review

Author(s)

Milhan, Noala Vicensoto Moreira ; Chiappim, William ; Sampaio, Aline da Graca ; Vegian, Mariana Raquel da Cruz ; Pessoa, Rodrigo Savio ; Koga-Ito, Cristiane Yumi

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; v. 23, n. 8, p. 26-pg., 2022-04-01.

Abstract

The activation of water by non-thermal plasma creates a liquid with active constituents referred to as plasma-activated water (PAW). Due to its active constituents, PAW may play an important role in different fields, such as agriculture, the food industry and healthcare. Plasma liquid technology has received attention in recent years due to its versatility and good potential, mainly focused on different health care purposes. This interest has extended to dentistry, since the use of a plasma-liquid technology could bring clinical advantages, compared to direct application of non-thermal atmospheric pressure plasmas (NTAPPs). The aim of this paper is to discuss the applicability of PAW in different areas of dentistry, according to the published literature about NTAPPs and plasma-liquid technology. The direct and indirect application of NTAPPs are presented in the introduction. Posteriorly, the main reactors for generating PAW and its active constituents with a role in biomedical applications are specified, followed by a section that discusses, in detail, the use of PAW as a tool for different oral diseases. (AU)

• FAPESP's process: 20/10450-7 - Exploring the potential of plasma activated liquid (PAL): characterization of plasma and application of PAL in endodontic treatment
• Grantee: William Chiappim Junior
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/25652-7 - Low-temperature plasma under atmospheric pressure as an adjuvant for the treatment of Oral Mucositis
• Grantee: Aline da Graça Sampaio
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 21/00046-7 - Association of L-ascorbic acid and cold atmospheric pressure plasma in the treatment of oral candidiasis: in vitro and in vivo evaluation
• Grantee: Noala Vicensoto Moreira Milhan
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/05856-7 - Use of low temperature atmospheric pressure plasma in dentistry: from laboratory bench to clinics
• Grantee: Cristiane Yumi Koga Ito
• Support Opportunities: Research Projects - Thematic Grants