| Full text | |
| Author(s): Show less - |
Tamara Rodrigues da Silva Destro
[1]
;
Thaís Marina Pires de Campos Biazon
[2]
;
Henrique Pott-Junior
[3]
;
Flávia Cristina Rossi Caruso
[4]
;
Daniela Kuguimoto Andaku
[5]
;
Naiara Molina Garcia
[6]
;
José Carlos Bonjorno-Junior
[7]
;
Audrey Borghi-Silva
[8]
;
Débora Mayumi de Oliveira Kawakami
[9]
;
Viviane Castello-Simões
[10]
;
Renata Gonçalves Mendes
[11]
Total Authors: 11
|
| Affiliation: Show less - | [1] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[2] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[3] Universidade Federal de São Carlos. Departamento de Medicina - Brasil
[4] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[5] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[6] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[7] Universidade Federal de São Carlos. Departamento de Medicina - Brasil
[8] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[9] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[10] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
[11] Universidade Federal de São Carlos. Departamento de Fisioterapia - Brasil
Total Affiliations: 11
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Terapia Intensiva; v. 34, n. 4, p. 461-468, 2023-03-03. |
| Abstract | |
ABSTRACT Objective: To investigate the influence of a passive mobilization session on endothelial function in patients with sepsis. Methods: This was a quasi-experimental double-blind and single-arm study with a pre- and postintervention design. Twenty-five patients with a diagnosis of sepsis who were hospitalized in the intensive care unit were included. Endothelial function was assessed at baseline (preintervention) and immediately postintervention by brachial artery ultrasonography. Flow mediated dilatation, peak blood flow velocity and peak shear rate were obtained. Passive mobilization consisted of bilateral mobilization (ankles, knees, hips, wrists, elbows and shoulders), with three sets of ten repetitions each, totaling 15 minutes. Results: After mobilization, we found increased vascular reactivity function compared to preintervention: absolute flow-mediated dilatation (0.57mm ± 0.22 versus 0.17mm ± 0.31; p < 0.001) and relative flow-mediated dilatation (17.1% ± 8.25 versus 5.08% ± 9.16; p < 0.001). Reactive hyperemia peak flow (71.8cm/s ± 29.3 versus 95.3cm/s ± 32.2; p < 0.001) and shear rate (211s ± 113 versus 288s ± 144; p < 0.001) were also increased. Conclusion: A passive mobilization session increases endothelial function in critical patients with sepsis. Future studies should investigate whether a mobilization program can be applied as a beneficial intervention for clinical improvement of endothelial function in patients hospitalized due to sepsis. (AU) | |
| FAPESP's process: | 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach |
| Grantee: | Audrey Borghi Silva |
| Support Opportunities: | Research Projects - Thematic Grants |