Nanotechnology-Based Dressings for Wound Management

Author(s)

Ataide, Janaina A. ; Zanchetta, Beatriz ; Santos, Erica M. ; Fava, Ana Laura M. ; Alves, Thais F. R. ; Cefali, Leticia C. ; Chaud, Marco, V ; Oliveira-Nascimento, Laura ; Souto, Eliana B. ; Mazzola, Priscila G.

• Document type: Journal article
• Source: PHARMACEUTICALS; v. 15, n. 10, p. 16-pg., 2022-10-01.

Abstract

Wound healing is known to be a complicated and intricate process and commonly classified as chronic or acute. Patients with chronic wounds are of public health concern, and require more attention onto skin lesions, including atopic dermatitis. Despite being a natural process, healing can be impaired by existing chronic de diseases such as diabetes, for example. Recently, wound dressings based in nanotechnology systems have emerged as a viable option to improve the healing process. Current advances in nanotechnology-based systems to release growth factors and bioactive agents represent a great opportunity to develop new therapies for wound treatments. It is essential that healthcare professionals understand the key processes involved in the healing cascade, to maximize care with these patients and minimize the undesirable outcomes of non-healing wounds. Therefore, this review aims to summarize the healing process phases and provide a general overview of dressings based in nanotechnology using biomaterials for the release of active agents in wound site. (AU)

• FAPESP's process: 15/15068-5 - DEVELOPMENT OF POLYMERIC PARTICLES AS CARRIER SYSTEMS FOR BIOACTIVE PRODUCTS
• Grantee: Janaína Artem Ataide
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 17/05275-9 - Bromelain encapsulation: stability, release profile, and cytotoxicity
• Grantee: Janaína Artem Ataide
• Support Opportunities: Scholarships abroad - Research Internship - Master's degree
• FAPESP's process: 18/07707-6 - Development of formulation for burns: analgesia, infection control and healing
• Grantee: Priscila Gava Mazzola
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/03444-5 - Development of healing pharmaceutical formulation containing bromelain extracted from industrial wastes
• Grantee: Priscila Gava Mazzola
• Support Opportunities: Regular Research Grants
• FAPESP's process: 20/11333-4 - Development of a polysaccharide membrane containing extract from the shell of Spondias mombin L. for the treatment of Pressure Ulcers
• Grantee: Érica Mendes dos Santos
• Support Opportunities: Scholarships in Brazil - Doctorate