Low-Noise Amplifier for Deep-Brain Stimulation (DBS)

Author(s)

Nordi, Tiago Matheus ; Gounella, Rodrigo Henrique ; Luppe, Maximiliam ; Soares Junior, Joao Navarro ; Fonoff, Erich Talamoni ; Colombari, Eduardo ; Romero, Murilo Araujo ; Pereira do Carmo, Joao Paulo

• Document type: Journal article
• Source: ELECTRONICS; v. 11, n. 6, p. 24-pg., 2022-03-01.

Abstract

Deep-brain stimulation (DBS) is an emerging research topic aiming to improve the quality of life of patients with brain diseases, and a great deal of effort has been focused on the development of implantable devices. This paper presents a low-noise amplifier (LNA) for the acquisition of biopotentials on DBS. This electronic module was designed in a low-voltage/low-power CMOS process, targeting implantable applications. The measurement results showed a gain of 38.6 dB and a -3 dB bandwidth of 2.3 kHz. The measurements also showed a power consumption of 2.8 mu W. Simulations showed an input-referred noise of 6.2 mu V-RMS. The LNA occupies a microdevice area of 122 mu m x 283 mu m, supporting its application in implanted systems. (AU)

• FAPESP's process: 19/05248-7 - CMOS microdevice to enable new brain stimulation therapies
• Grantee: João Paulo Pereira Do Carmo
• Support Opportunities: Regular Research Grants