Post-dynamic, isometric and combined resistance exercise responses in medicated hypertensive men

Author(s)

Oliveira-Silva, Laura ; Fecchio, Rafael Yokoyama ; da Silva Junior, Natan Daniel ; Pio-Abreu, Andrea ; da Silva, Giovanio Vieira ; Drager, Luciano Ferreira ; de Sousa, Julio Cesar Silva ; de Moraes Forjaz, Claudia Lucia

• Document type: Journal article
• Source: JOURNAL OF HUMAN HYPERTENSION; v. N/A, p. 10-pg., 2023-09-05.

Abstract

This study investigated the effects of dynamic resistance exercise (DRE), isometric handgrip exercise (IHE) and combined resistance exercise (DRE+IHE) on post-exercise hypotension (PEH) and its hemodynamic, autonomic, and vascular mechanisms. For that, 70 medicated hypertensives men (52 +/- 8 years) were randomly allocated to perform one of the following interventions: DRE (3 sets, 8 exercises, 50% of 1RM), IHE (4 sets, 2 min, 30% of MVC), CRE (DRE+IHE) and control (CON, seated rest). Before and after the interventions, blood pressure (BP), systemic hemodynamics, cardiovascular autonomic modulation and brachial vascular parameters were evaluated. After the DRE and CRE, systolic and mean BP decreased (SBP = -7 +/- 6 and -8 +/- 8 mmHg; MBP -4 +/- 5 and -5 +/- 5 mmHg, respectively, all P < 0.05), vascular conductance increased (+ 0.47 +/- 0.61 and +0.40 +/- 0.47 ml.min(-1).mmHg(-1), respectively, both P < 0.05) and baroreflex sensitivity decreased (-0.15 +/- 0.38 and -0.29 +/- 0.47 ms/mmHg, respectively, both P < 0.05) in comparison to pre-exercise values. No variable presented any significant change after IHE. The responses observed after CRE were similar to DRE and significantly different from CON and IHE. In conclusion, DRE, but not IHE, elicits PEH, which happens concomitantly to skeletal muscle vasodilation and decreased baroreflex sensitivity. Moreover, adding IHE to DRE does not potentiate PEH and neither changes its mechanisms. (AU)

• FAPESP's process: 18/12390-1 - Effects of dynamic, isometric and combined (dynamic + isometric) resistance training on resting and post-exercise cardiovascular function and regulation in medicated hypertensive men
• Grantee: Rafael Yokoyama Fecchio
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 19/02649-0 - Acute hypotensive effect of dynamic, isometric and combined (dynamic + isometric) resistance exercise in medicated hypertensives men: hemodynamic and autonomic mechanisms
• Grantee: Laura Gomes Oliveira e Silva
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 18/23653-3 - Acute hypotensive effect of dynamic, isometric and combined (dynamic + isometric)resistance exercise in medicated hypertensives men: hemodynamic and autonomic mechanisms
• Grantee: Cláudia Lúcia de Moraes Forjaz
• Support Opportunities: Regular Research Grants