| Full text | |
| Author(s): Show less - |
Weidmann, Manfred
;
Frey, Stefan
;
Freire, Caio C. M.
;
Essbauer, Sandra
;
Ruzek, Daniel
;
Klempa, Boris
;
Zubrikova, Dana
;
Voegerl, Maria
;
Pfeffer, Martin
;
Hufert, Frank T.
;
Zanotto, Paolo M.
;
Dobler, Gerhard
Total Authors: 12
|
| Document type: | Journal article |
| Source: | JOURNAL OF GENERAL VIROLOGY; v. 94, p. 11-pg., 2013-09-01. |
| Abstract | |
In order to obtain a better understanding of tick-borne encephalitis virus (TBEV) strain movements in central Europe the E gene sequences of 102 TBEV strains collected from 1953 to 2011 at 38 sites in the Czech Republic, Slovakia, Austria and Germany were determined. Bayesian analysis suggests a 350-year history of evolution and spread in central Europe of two main lineages, A and B. In contrast to the east to west spread at the Eurasian continent level, local central European spreading patterns suggest historic west to east spread followed by more recent east to west spread. The phylogenetic and network analyses indicate TBEV ingressions from the Czech Republic and Slovakia into Germany via landscape features (Danube river system), biogenic factors (birds, red deer) and anthropogenic factors. The identification of endemic foci showing local genetic diversity is of paramount importance to the field as these will be a prerequisite for in-depth analysis of focal TBEV maintenance and long-distance TBEV spread. (AU) | |
| FAPESP's process: | 10/19341-4 - Biological characterization of natural and artificial HIV-1 recombinants between subtypes B and F |
| Grantee: | Paolo Marinho de Andrade Zanotto |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 11/17120-3 - Genetic diversity analysis of nucleopolyhedrovirus Anticarsia gemmatalis (AgMNPV) populations isolated in different geographic regions |
| Grantee: | Paolo Marinho de Andrade Zanotto |
| Support Opportunities: | Regular Research Grants |