Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam

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Author(s):	Borges, Maiara S. ; Biasetto, Carolina R. ; Chapla, Vanessa M. ; Ebrahimi, Samad N. ; Costa, Mayra F. ; Bolzani, Vanderlan S. ; Araujo, Angela R. Total Authors: 7
Document type:	Journal article
Source:	Journal of the Brazilian Chemical Society; v. 30, n. 3, p. 6-pg., 2019-03-01.
Abstract
A new compound named methyl (6S,7S,2E,4E)-6,7-dihydroxy-4,6-dimethyl octanoate was isolated from Saccharicola sp. using high performance liquid chromatography-solid phase extraction-transfer tube (HPLC-SPE-TT), together with four known compounds, fusaric acid, trans-4-hydroxymellein, thymidine and adenosine. Saccharicola sp. was isolated from the stems of Eugenia jambolana Lam. (Myrtaceae) as endophytic fungus. The structure of this novel substance was established based on its spectroscopic data, including H-1 and C-13 nuclear magnetic resonance (NMR), 2D NMR techniques and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS). This paper deals with the first report of its kind on this compound in Saccharicola sp. (AU)

FAPESP's process:	13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:	Glaucius Oliva
Support Opportunities:	Research Grants - Research, Innovation and Dissemination Centers - RIDC


FAPESP's process:	14/50926-0 - INCT 2014: biodiversity and natural products
Grantee:	Vanderlan da Silva Bolzani
Support Opportunities:	BIOTA-FAPESP Program - Thematic Grants