| Full text | |
| Author(s): |
do Nascimento Pomari, Andreia Aparecida
;
do Amaral Montanheiro, Thais Larissa
;
de Siqueira, Cristiane Pereira
;
Silva, Rodrigo Sousa
;
Tada, Dayane Batista
;
Lemes, Ana Paula
Total Authors: 6
|
| Document type: | Journal article |
| Source: | JOURNAL OF COMPOSITES SCIENCE; v. 3, n. 3, p. 12-pg., 2019-09-01. |
| Abstract | |
In this work, chitosan hydrogels crosslinked with genipin and reinforced with cellulose nanocrystals (CNC) were developed and characterized with the aim of future biomedical applications. CNC was produced by acid hydrolysis and characterized by atomic force microscopy (AFM). Chitosan/CNC nanocomposite hydrogels were produced with different CNC concentrations (w/w): 0%, 2%, 4%, and 6%. The genipin was used as a crosslinking agent in a genipin/chitosan molar proportion of 1:8. The hydrogels were characterized by porosity measurements, scanning electron microscopy (SEM), swelling test, and mechanical compression test. No significant differences were observed concerning the porosity of the hydrogels; however, a trend of decreasing porosity was observed with increasing CNC content. The SEM images showed a better pore structure as the CNC concentration increased. A decrease in the swelling degree with increasing CNC content in the chitosan/CNC nanocomposite hydrogel was verified in the swelling tests. An increase in the CNC concentration in the chitosan/CNC nanocomposite hydrogel caused a gradual increase in the maximum stress and maximum strain as observed in the compression tests, showing a significant di fference between chitosan /CNC 6 wt % and neat chitosan hydrogel. (AU) | |
| FAPESP's process: | 11/23895-8 - Characterization and control of cellular internalization process of nanoparticles |
| Grantee: | Dayane Batista Tada |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 13/27064-9 - Utilization of cellulose nanocrystals in the production of polymer nanocomposites for applications in the medical area |
| Grantee: | Ana Paula Lemes |
| Support Opportunities: | Regular Research Grants |