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Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

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Author(s):
Lima, Cassio A. ; Correa, Luciana ; Byrne, Hugh J. ; Zezell, Denise M. ; Brown, JC ; VanLeeuwen, TG
Total Authors: 6
Document type: Journal article
Source: CLINICAL AND PRECLINICAL OPTICAL DIAGNOSTICS II; v. 11073, p. 3-pg., 2019-01-01.
Abstract

Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin. (AU)

FAPESP's process: 05/51689-2 - Optics and Photonics Research Center at UNICAMP
Grantee:Hugo Luis Fragnito
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC