| Full text | |
| Author(s): |
Hassan, Ayaz
;
de Sousa, Daniel S.
;
Bertaglia, Thiago
;
Crespilho, Frank N.
Total Authors: 4
|
| Document type: | Journal article |
| Source: | CHEMICAL COMMUNICATIONS; v. 60, n. 56, p. 4-pg., 2024-06-06. |
| Abstract | |
A label-free one-step lithographically masked deposition technique was implemented for the fabrication of gold nanoparticle (Au NP) micropatterns. These micropatterns serve as active substrates for surface-enhanced infrared absorption spectroscopy (SEIRAS) and exhibit a substantial increase in the IR signal upon adsorption of multiple proteins compared to untreated surfaces. Micro-FTIR chemical imaging was conducted to evaluate the efficacy of Au NP micropatterns as singular enhancers for SEIRAS across diverse IR-active substrates demonstrating a promising application for the detection of proteins at low concentrations within biological fluids. An average of 7.5 times enhancement in the IR absorption signal is observed for cytochrome c adsorbed on gold nanoparticle micropatterns as compared to a bare infrared surface in surface enhanced infrared spectroscopy. (AU) | |
| FAPESP's process: | 19/12053-8 - High Performance Electrodes Applied in Organic Batteries and in Biofuel Cell |
| Grantee: | Frank Nelson Crespilho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 19/15333-1 - Bio-Photo-Electrochemical Hybrid Cells for Solar Energy Conversion |
| Grantee: | Frank Nelson Crespilho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 18/22214-6 - Toward a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis |
| Grantee: | Osvaldo Novais de Oliveira Junior |
| Support Opportunities: | Research Projects - Thematic Grants |