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Is the carotenoid production from Phaffia rhodozyma yeast genuinely sustainable? a comprehensive analysis of biocompatibility, environmental assessment, and techno-economic constraints

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Author(s):
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Mussagy, Cassamo U. ; Dias, Ana C. R. V. ; Santos-Ebinuma, Valeria C. ; Sadek, M. Shaaban ; Ahmad, Mushtaq ; de Andrade, Cleverton R. ; Haddad, Felipe F. ; dos Santos, Jean L. ; Scarim, Caue B. ; Pereira, Jorge F. B. ; Floriano, Juliana Ferreira ; Herculano, Rondinelli D. ; Mustafa, Ahmad
Total Authors: 13
Document type: Journal article
Source: Bioresource Technology; v. 397, p. 12-pg., 2024-02-19.
Abstract

8-carotene. However, the shift from academic exploration to effective industrial implementation has been challenging to achieve. This study aims to bridge this gap by assessing various scenarios for carotenoid production and recovery. It explores the use of ionic liquids (ILs) and bio-based solvents (ethanol) to ensure safe extraction. The evaluation includes a comprehensive analysis involving Life Cycle Assessment (LCA), biocompatibility assessment, and Techno-Economic Analysis (TEA) of two integrated technologies that utilize cholinebased ILs and ethanol (EtOH) for astaxanthin (+8-carotene) recovery from P. rhodozyma cells. This work evaluates the potential sustainability of integrating these alternative solvents within a yeast-based bioeconomy. (AU)

FAPESP's process: 21/06686-8 - Biotechnological process for the development of natural colorants from microbial sources for industrial application: phase II
Grantee:Valéria de Carvalho Santos Ebinuma
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Young Investigators Grants - Phase 2
FAPESP's process: 23/01368-3 - Stabilization and encapsulation of natural colorants and application in the development of packaging and cosmetics
Grantee:Valéria de Carvalho Santos Ebinuma
Support Opportunities: Regular Research Grants