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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

FIRST OCCURRENCE OF AN AUTOCHTHONOUS CANINE CASE OF Leishmania (Leishmania) infantum chagasi IN THE MUNICIPALITY OF CAMPINAS, STATE OF SAO PAULO, BRAZIL

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Author(s):
Mouriz Savani, Elisa San Martin [1] ; Presotto, Douglas [2] ; Roberto, Thais [3] ; Gibrail de Oliveira Camargo, Maria Ceclia [1] ; Nicoletti D'Auria, Sandra Regina [1] ; Sacramento, Debora Veiga [4]
Total Authors: 6
Affiliation:
[1] Ctr Controle Zoonoses Municipio Sao Paulo, BR-02031020 Sao Paulo - Brazil
[2] Ctr Controle Zoonoses Municipio Campinas, Campinas, SP - Brazil
[3] Hosp Vet Taquaral, Campinas, SP - Brazil
[4] Genom Engn Mol, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Revista do Instituto de Medicina Tropical de São Paulo; v. 53, n. 4, p. 227-229, JUL-AUG 2011.
Web of Science Citations: 3
Abstract

An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA-based nested-PCR assay. The PCR product, a 490 bp fragment, was sequenced and the nucleotide sequence was identical to that of Leishmania (Leishmania) infantum chagasi. These results are surprising since no autochthonous human or canine cases of visceral leishmaniasis have ever been reported in this municipality. This case suggests that natural transmission of this disease is occurring in this area. (AU)