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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evolutionary history of Dengue virus type 4: Insights into genotype phylodynamics

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Author(s):
Villabona-Arenas, Christian Julian [1] ; de Andrade Zanotto, Paolo Marinho [1]
Total Authors: 2
Affiliation:
[1] Univ Sao Paulo, Dept Microbiol, Inst Biomed Sci, Lab Mol Evolut & Bioinformat, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: INFECTION GENETICS AND EVOLUTION; v. 11, n. 5, p. 878-885, JUL 2011.
Web of Science Citations: 24
Abstract

Dengue virus type 4 (DENV-4) circulates in tropical and subtropical countries from Asia and the Americas. Despite the importance of dengue virus distribution, little is known about the worldwide viral spread. Following a Bayesian phylogenetic approach we inferred the evolutionary history of 310 isolates sampled from 37 countries during the time period 1956-2008 and the spreading dynamics for genotypes I and II. The region (tropical rainforest biome) comprised by Malaysia-Thailand was the most likely ancestral area from which the serotype has originated and spread. Interestingly, cross-correlation analysis on demographic time series with the Asian sequences showed a statistically significant negative correlation that could be suggestive of competition among genotypes within the same serotype. (C) 2011 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 08/10713-6 - Structural proteome and characterization of ORF-31 product of the nucleopolyhedrovirus Anticarsia gemmatalis (AgMNPV-2D) in different cell lines
Grantee:Paolo Marinho de Andrade Zanotto
Support Opportunities: Regular Research Grants