| Full text | |
| Author(s): |
Ratzke, Roberto
[1]
;
Moreno, Doris Hupfeld
[2, 3]
;
Gorenstein, Clarice
[4]
;
Moreno, Ricardo Alberto
[2, 3]
Total Authors: 4
|
| Affiliation: | [1] Univ Fed Parana, BR-80060000 Curitiba, Parana - Brazil
[2] Univ Sao Paulo, Sch Med, Mood Disorders Unit GRUDA, Dept Psychiat, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Mood Disorders Unit GRUDA, Inst Psychiat, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Pharmacol, Inst Biomed Sci, Inst Psychiat, Lab Clin & Expt Psychopharmacol Med Invest 23, Sao Paulo - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Psiquiatria; v. 33, n. 1, p. 64-67, MAR 2011. |
| Web of Science Citations: | 2 |
| Abstract | |
Objective: The aim of this study was to translate the Structured Clinical Interview for Mood Spectrum into Brazilian Portuguese, measuring its reliability, validity, and defining scores for bipolar disorders. Method: Questionnaire was translated (into Brazilian Portuguese) and back-translated into English. Sample consisted of 47 subjects with bipolar disorder, 47 with major depressive disorder, 18 with schizophrenia and 22 controls. Inter-rater reliability was tested in 20 subjects with bipolar disorder and MDD. Internal consistency was measured using the Kuder Richardson formula. Forward stepwise discriminant analysis was performed. Scores were compared between groups; manic (M), depressive (D) and total (T) threshold scores were calculated through receiver operating characteristic (ROC) curves. Results: Kuder Richardson coefficients were between 0.86 and 0.94. Intraclass correlation coefficient was 0.96 (Cl 95 % 0.93-0.97). Subjects with bipolar disorder had higher M and T, and similar D scores, when compared to major depressive disorder (ANOVA, p < 0.001). The sub-domains that best discriminated unipolar and bipolar subjects were manic energy and manic mood. M had the best area under the curve (0.909), and values of M equal to or greater than 30 yielded 91.5% sensitivity and 74.5% specificity. Conclusion: Structured Clinical Interview for Mood Spectrum has good reliability and validity. Cut-off of 30 best differentiates subjects with bipolar disorder vs. unipolar depression. A cutoff score of 30 or higher in the mania subdomain is appropriate to help make a distinction between subjects with bipolar disorder and those with unipolar depression. (AU) | |
| FAPESP's process: | 01/00189-9 - A psychobiological study of emotional regulation based on the effects of antidepressant drugs |
| Grantee: | Valentim Gentil Filho |
| Support Opportunities: | Research Projects - Thematic Grants |