| Full text | |
| Author(s): |
Andrade, Celi Santos
;
Leite, Claudia da Costa
[1]
Total Authors: 2
|
| Affiliation: | [1] Univ Sao Paulo, Inst Radiol, Setor Ressonancia Magnet, Radiol Dept, Sch Med, BR-05403001 Sao Paulo - Brazil
Total Affiliations: 1
|
| Document type: | Review article |
| Source: | Arquivos de Neuro-Psiquiatria; v. 69, n. 1, p. 130-138, FEB 2011. |
| Web of Science Citations: | 12 |
| Abstract | |
Malformations of cortical development (MCD) result from disruptions in the complex process of the human brain cortex formation and are highly associated to severe epilepsy, neurodevelopmental delay and motor dysfunction. Nowadays, magnetic resonance imaging (MRI) is the cornerstone of the work-up of patients with epilepsy and modern advanced imaging techniques have improved not only our ability to detect and characterize cortical malformations, but also in identifying associated functional abnormalities that are far beyond the structural visualized lesions. Herein, we address the most currently used classifications of MCD and make a concise review of the embryological process of cortical development. Our main goal is to summarize recent advances and new trends in diagnostic imaging techniques concerning MCD. Thereafter, follows a brief discussion of specific disorders and their radiological features. (AU) | |
| FAPESP's process: | 05/56464-9 - Neuroscience Imaging Center at University of São Paulo Medical School |
| Grantee: | Giovanni Guido Cerri |
| Support Opportunities: | Inter-institutional Cooperation in Support of Brain Research (CINAPCE) - Thematic Grants |