Effects of childhood development on late-life mental disorders

Author(s)

Salum, Giovanni A. ^[1] ; Polanczyk, Guilherme V. ^{[1, 2]} ; Miguel, Euripedes C. ^{[1, 2]} ; Rohde, Luis A. P. ^{[1, 3]}

Affiliation

^[1] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Natl Inst Dev Psychiat Childhood & Adolescence IN, BR-90035003 Porto Alegre, RS - Brazil

^[2] Univ Sao Paulo Med Sch, Dept Psychiat, Sao Paulo - Brazil

^[3] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Child Psychiat Div, BR-90035003 Porto Alegre, RS - Brazil

• Document type: Journal article
• Source: CURRENT OPINION IN PSYCHIATRY; v. 23, n. 6, p. 498-503, NOV 2010.
• Web of Science Citations: 19

Abstract

Purpose of review To explore recent findings bridging childhood development and common late-life mental disorders in the elderly. Recent findings We addressed aging as a part of the developmental process in central nervous system, typical and atypical neurodevelopment focusing on genetic and environmental risk factors and their interplay and links between psychopathology from childhood to the elderly, unifying theoretical perspectives and preventive intervention strategies. Summary Current findings suggest that childhood development is strictly connected to psychiatric phenotypes across the lifespan. Although we are far from a comprehensive understanding of mental health trajectories, some initial findings document both heterotypic and homotypic continuities from childhood to adulthood and from adulthood to the elderly. Our review also highlights the urgent need for investigations on preventive interventions in individuals at risk for mental disorders. (AU)

• FAPESP's process: 08/57896-8 - National Institute for Developmental Psychiatry
• Grantee: Eurípedes Constantino Miguel Filho
• Support Opportunities: Research Projects - Thematic Grants