| Full text | |
| Author(s): |
Chavez-Jauregui, Rosa Nilda
[1]
;
Santos, Raul Dias
[2]
;
Macedo, Alessandra
[2]
;
Marte Chacra, Ana Paula
[1]
;
Martinez, Tania Leme
[1]
;
Gomes Areas, Jose Alfredo
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo USP, Fac Saude Publ, Dept Nutr, BR-01246904 Sao Paulo - Brazil
[2] Univ Sao Paulo Usp, Inst Coracao, Fac Med, Inst Coracao, BR-01246904 Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | FOOD SCIENCE AND TECHNOLOGY; v. 30, n. 4, p. 1007-1010, OCT-DEC 2010. |
| Web of Science Citations: | 2 |
| Abstract | |
We evaluated the effects of defatted amaranth (Amaranthus caudatus L.) snacks on plasma lipids in moderate hypercholesterolemic patients. Twenty-two subjects [30-65 years old), 11 males, with total cholesterol (TC) > 240 mg.dL-1, low-density cholesterol (LDL-c) 160-190 mg.dL-1 and plasma triglycerides (TG) < 400 mg.dL-1] were randomized in a double blind clinical trial to receive an amaranth snack (50 g/day) or equivalent corn snack (placebo) for 2 months. There were no differences between amaranth and placebo on TC and LDL-c, and TG respectively: -8.4 and -5.7% (p = 0.17); -12.3 and -9.7% (p = 0.41) and -0.6 and -7.3% (p = 0.47). However, amaranth snacks significantly reduced high-density cholesterol (HDL-c): -15.2 vs. -4% (p = 0.03). In conclusion, the intake of 50 g of extruded amaranth daily during 60 days did not significantly reduce LDL-c in moderate hypercholesterolemic subjects; furthermore there was a significant reduction in HDL-c. Studies with greater number of subjects and greater quantity of this food are necessary to test the effects of amaranth on lipid metabolism in humans. (AU) | |
| FAPESP's process: | 98/08095-9 - Nutrition and health: an integrated approach for nutritional evaluation, development of foods for special purposes and nutritional intervention |
| Grantee: | José Alfredo Gomes Arêas |
| Support Opportunities: | Research Projects - Thematic Grants |