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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Treatment of obstructive sleep apnea syndrome in patients from a teaching hospital in Brazil: is it possible?

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Author(s):
Polizel Ranieri, Ana Laura [1] ; Costa Pereira Jales, Sumatra Melo [1] ; Simoes Formigoni, Gilberto Guanaes [2] ; de Aloe, Flavio Sadurny [3, 4] ; Azevedo Tavares, Stella Marcia [3, 4] ; Tesseroli Siqueira, Jose Tadeu [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Sch Med, Hosp Clin, Dent Div, Cent Inst, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Med, Hosp Clin, Otorrinolaringol Dept, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Hosp Clin, Ctr Sleep Wake Disorders, Sao Paulo - Brazil
[4] Univ Sao Paulo, Inst Psychiat, Ctr Sleep Wake Disorders, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Sleep and Breathing; v. 13, n. 2, p. 121-125, MAY 2009.
Web of Science Citations: 1
Abstract

The aim of this study was to evaluate the efficacy of a cost-effective intra-oral appliance for obstructive sleep apnea syndrome built into a large teaching hospital. Out of 20 evaluated and treated patients, 14 concluded the study: eight men and six women, with a mean age of 42-46 (mean + SD) years and mean body mass index of 27.66. Inclusion criteria were mild or moderate apnea-hypopnea index (AHI) according to a polysomnographic study. All patients were treated with the monobloco intra-oral appliance. They were then submitted to a follow-up polysomnographic study after 60 days using the appliance. An orofacial clinical evaluation was carried out with the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) questionnaire and with clinical evaluation questionnaire devised by the Orofacial Pain Team before and 60 days after fitting the intra-oral appliance. The AHI showed a statistically meaningful (p = 0.002) reduction from 15.53 to 7.82 events per hour, a non-statistically significant oxygen saturation increase from 83.36 to 84.86 (p = 0.09), and Epworth's sleepiness scale reduction from 9.14 to 6.36 (p = 0.001). Three patients did not show any improvement. The most common side effect during the use of the appliance/device was pain and facial discomfort (28.57%), without myofascial or temporomandibular joint pain as evaluated by the RDC/TMD questionnaire. The intra-oral device produced a significant reduction of the apnea-hypopnea index during the study period with the use of the monobloco intra-oral appliance. Patients did not show prior myofascial pain or 60 days after use of the intra-oral appliance. (AU)

FAPESP's process: 07/06792-5 - Evaluation of the effectiveness of intra-oral device in the treatment of the Obstructive Sleep Apnea Syndrome in education hospital.
Grantee:Ana Laura Polizel Ranieri
Support Opportunities: Scholarships in Brazil - Master