Treatment of obstructive sleep apnea syndrome in patients from a teaching hospital in Brazil: is it possible?

Author(s)

Polizel Ranieri, Ana Laura ^[1] ; Costa Pereira Jales, Sumatra Melo ^[1] ; Simoes Formigoni, Gilberto Guanaes ^[2] ; de Aloe, Flavio Sadurny ^{[3, 4]} ; Azevedo Tavares, Stella Marcia ^{[3, 4]} ; Tesseroli Siqueira, Jose Tadeu ^[1]

Affiliation

^[1] Univ Sao Paulo, Sch Med, Hosp Clin, Dent Div, Cent Inst, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Med, Hosp Clin, Otorrinolaringol Dept, Sao Paulo - Brazil

^[3] Univ Sao Paulo, Sch Med, Hosp Clin, Ctr Sleep Wake Disorders, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Inst Psychiat, Ctr Sleep Wake Disorders, Sao Paulo - Brazil

• Document type: Journal article
• Source: Sleep and Breathing; v. 13, n. 2, p. 121-125, MAY 2009.
• Web of Science Citations: 1

Abstract

The aim of this study was to evaluate the efficacy of a cost-effective intra-oral appliance for obstructive sleep apnea syndrome built into a large teaching hospital. Out of 20 evaluated and treated patients, 14 concluded the study: eight men and six women, with a mean age of 42-46 (mean + SD) years and mean body mass index of 27.66. Inclusion criteria were mild or moderate apnea-hypopnea index (AHI) according to a polysomnographic study. All patients were treated with the monobloco intra-oral appliance. They were then submitted to a follow-up polysomnographic study after 60 days using the appliance. An orofacial clinical evaluation was carried out with the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) questionnaire and with clinical evaluation questionnaire devised by the Orofacial Pain Team before and 60 days after fitting the intra-oral appliance. The AHI showed a statistically meaningful (p = 0.002) reduction from 15.53 to 7.82 events per hour, a non-statistically significant oxygen saturation increase from 83.36 to 84.86 (p = 0.09), and Epworth's sleepiness scale reduction from 9.14 to 6.36 (p = 0.001). Three patients did not show any improvement. The most common side effect during the use of the appliance/device was pain and facial discomfort (28.57%), without myofascial or temporomandibular joint pain as evaluated by the RDC/TMD questionnaire. The intra-oral device produced a significant reduction of the apnea-hypopnea index during the study period with the use of the monobloco intra-oral appliance. Patients did not show prior myofascial pain or 60 days after use of the intra-oral appliance. (AU)

• FAPESP's process: 07/06792-5 - Evaluation of the effectiveness of intra-oral device in the treatment of the Obstructive Sleep Apnea Syndrome in education hospital.
• Grantee: Ana Laura Polizel Ranieri
• Support Opportunities: Scholarships in Brazil - Master