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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Ultrastructural characteristics of the gerbil pterygoid medial muscle after experimental occlusal alteration

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Author(s):
Iyomasa, Mamie Mizusaki [1] ; Mardegan Issa, Joao Paulo [1] ; Kronka Sosthines, Marcia Consentino [2] ; De Oliveira, Ana Maria [3] ; Sasso Stuani, Maria Bernadete [1] ; Motoyama, Aracy Akiko [4] ; Watanabe, Ii-Sei [4]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Fac Dent Ribeirao Preto, Sao Paulo - Brazil
[2] Univ Belem, Morphofunct Inst, Belem, Para - Brazil
[3] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto, Sao Paulo - Brazil
[4] Univ Sao Paulo, Inst Biomed Sci, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Review article
Source: Micron; v. 40, n. 2, p. 206-211, FEB 2009.
Web of Science Citations: 6
Abstract

Ten male young adult gerbils Meriones unguiculatus weighing 55 g were divided in two groups: experimental (n = 5) animals submitted to exodontia of the left upper molars, and sham-operated were used as control (n = 5) group. The aim of the present study was to investigate the ultrastructural effects of occlusal alteration induced by unilateral exodontia on medial pterygoid muscle. After 60 days, the animals were sacrificed by perfusion intracardially with a modified Karnovsky solution after anesthetized with overdose of urethane (3 g/kg i.p.). The small samples of this muscle were fixed in 2.5% glutaraldehyde solution and post-fixed in 1% buffered osmium tetroxide solution, dehydrated in ascending concentration of ethanol, and embedded in Spurr resin. Several micrographs data showed that in this period of time, the unilateral teeth extraction was able to induce modifications on the medial pterygoid muscle fibers and capillaries at ultrastructural levels as compared to control muscles and to the ones in the contralateral side of the experimental animals. Ultrastructural changes suggest that injury was greater in the hypofunctional Muscle, ipsilateral to teeth extraction. (c) 2008 Elsevier Ltd. All rights reserved. (AU)