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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties

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Author(s):
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Moreira, Leonardo M. [1] ; Lima, Adriana [1] ; Soares, Rafael R. S. [2] ; Batistela, Vagner R. [2] ; Gerola, Adriana P. [2] ; Hioka, Noboru [2] ; Bonacin, Juliano A. [3] ; Severino, Divinomar [3] ; Baptista, Mauricio S. [3] ; da Hora Machado, Antonio E. [4] ; Rodrigues, Maira R. [1] ; Codognoto, Lucia [1] ; de Oliveira, Hueder P. M. [1]
Total Authors: 13
Affiliation:
[1] Univ Camilo Castelo Branco, BR-12247004 Sao Jose Dos Campos - Brazil
[2] Univ Estadual Maringa, Dept Quim, BR-87020900 Maringa, Parana - Brazil
[3] Univ Sao Paulo, Dept Bioquim, Inst Quim, BR-05508900 Sao Paulo - Brazil
[4] Univ Fed Uberlandia, Inst Quim, BR-38408100 Uberlandia, MG - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 20, n. 9, p. 1653-1658, 2009.
Web of Science Citations: 13
Abstract

In this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy. (AU)