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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Objective characterization of the course of the parasellar internal carotid artery using mathematical tools

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Author(s):
Meng, Stefan [1, 2] ; Geyer, Stefan H. [1] ; Costa, Luciano da F. [3] ; Viana, Matheus P. [3] ; Weninger, Wolfgang J. [1]
Total Authors: 5
Affiliation:
[1] Med Univ Vienna, Ctr Anat & Cell Biol, IMG, A-1090 Vienna - Austria
[2] Kaiser Franz Joseph Spital, Dept Radiol, A-1100 Vienna - Austria
[3] Univ Sao Paulo, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: SURGICAL AND RADIOLOGIC ANATOMY; v. 30, n. 6, p. 519-526, AUG 2008.
Web of Science Citations: 12
Abstract

Background Along the internal carotid artery (ICA), atherosclerotic plaques are often located in its cavernous sinus (parasellar) segments (pICA). Studies indicate that the incidence of pre-atherosclerotic lesions is linked with the complexity of the pICA; however, the pICA shape was never objectively characterized. Our study aims at providing objective mathematical characterizations of the pICA shape. Methods and results Three-dimensional (3D) computer models, reconstructed from contrast enhanced computed tomography (CT) data of 30 randomly selected patients (60 pICAs) were analyzed with modern visualization software and new mathematical algorithms. As objective measures for the pICA shape complexity, we provide calculations of curvature energy, torsion energy, and total complexity of 3D skeletons of the pICA lumen. We further measured the posterior knee of the so-called ``carotid siphon{''} with a virtual goniometer and performed correlations between the objective mathematical calculations and the subjective angle measurements. Conclusions Firstly, our study provides mathematical characterizations of the pICA shape, which can serve as objective reference data for analyzing connections between pICA shape complexity and vascular diseases. Secondly, we provide an objective method for creating Such data. Thirdly, we evaluate the usefulness of subjective goniometric measurements of the angle of the posterior knee of the carotid siphon. (AU)

FAPESP's process: 05/00587-5 - Mesh (graph) modeling and techniques of pattern recognition: structure, dynamics and applications
Grantee:Roberto Marcondes Cesar Junior
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 07/50882-9 - Characterization and modeling of biological networks
Grantee:Matheus Palhares Viana
Support Opportunities: Scholarships in Brazil - Doctorate